Severe coronavirus disease-2019 (COVID-19) can progress to an acute respiratory distress syndrome (ARDS), which involves alveolar infiltration by activated neutrophils. The beta-blocker metoprolol has been shown to ameliorate exacerbated inflammation in the myocardial infarction setting.

Centro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid, Spain Drs Clemente-Moragón and Martínez-Milla contributed equally to this work.