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Mini-Brain Study Shows How Environmental Risk Factors Can Amplify Genetic Risks for Autism

Posted in biotech/medical, genetics, health, neuroscience

Summary: Using human stem cells to develop a brain organoid model, researchers were able to show exposure to a common pesticide synergizes with an autism-linked gene mutation. The study provides clear evidence that genetics and environment may combine to disrupt neurodevelopment.

Source: Johns Hopkins University.

Researchers at Johns Hopkins Bloomberg School of Public Health have shown in a brain organoid study that exposure to a common pesticide synergizes with a frequent autism-linked gene mutation.

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