:ooooo.

What is CAR-T therapy?

CAR-T therapy involves genetically engineering patient T-cells so that they express a chimeric antigen receptor (CAR).

CARs consist of a protein that binds to cancer cells, usually an antibody, fused to the signaling domain from a T-cell receptor (TCR). The idea is that a killer T-cell expressing the CAR engages cancer cells and eliminates them.