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Scientists Explore Molecular Connections Between Genetics, Gut Microbiome, and Memory

A molecule commonly produced by gut microbes appears to improve memory in mice.

A new study is among the first to trace the molecular connections between genetics, the gut microbiome, and memory in a mouse model bred to resemble the diversity of the human population.

While tantalizing links between the gut microbiome and brain have previously been found, a team of researchers from two U.S. Department of Energy national laboratories found new evidence of tangible connections between the gut and the brain. The team identified lactate, a molecule produced by all species of one gut microbe, as a key memory-boosting molecular messenger. The work was published recently in the journal BMC Microbiome.

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