Summary: Tau spreads through the human brain via neural communication pathways. The spread is accelerated by the presence of amyloid-beta.

Source: Lund University

Toxic versions of the protein tau are believed to cause death of neurons of the brain in Alzheimer’s disease. A new study published in Nature Communications shows that the spread of toxic tau in the human brain in elderly individuals may occur via connected neurons. The researchers could see that beta-amyloid facilitates the spread of toxic tau.