Two Nature papers show that it is possible to make T cells that target some of the few neoantigens expressed by glioblastomas and that T- cell responses can be boosted in cancers. This News & Views discusses the findings.
Clinical trials reveal that personalized vaccines can boost immune-cell responses to brain tumours that don’t usually respond to immunotherapy. The findings also point to how to improve such treatments. Personalized vaccines boost immune responses targeting brain tumours.
Read more