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Month: September 2018

Patients want to see their medical information. Researchers want to share their data.

Now, scientists at Scripps Research have released a new technology designed to make these measurements easier to perform and more accessible to practitioners, scientists and the general public.

“This is really about data sharing and accelerating the process of discovery,” says Gary Siuzdak, Ph.D., professor at Scripps Research and co-corresponding author of the new XCMS/METLIN open data analysis platform, published recently in Nature Methods.

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A tiny laser comprising an array of nanoscale semiconductor cylinders (see image) has been made by an all-A*STAR team. This is the first time that lasing has been achieved in non-metallic nanostructures, and it promises to lead to miniature lasers usable in a wide range of optoelectronic devices.

Microscale lasers are widely used in devices such as CD and DVD players. Now, optical engineers are developing nanoscale lasers—so small that they cannot be seen by the human eye.

A promising method is to use arrays of made from semiconductors with a high refractive index. Such structures act as tiny antennas, resonating at specific wavelengths. However, it has been challenging to use them to construct a cavity—the heart of a laser, where light bounces around while being amplified.

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An international team of researchers led by The Australian National University (ANU) has invented a tiny camera lens, which may lead to a device that links quantum computers to an optical fibre network.

Quantum computers promise a new era in ultra-secure networks, artificial intelligence and therapeutic drugs, and will be able to solve certain problems much faster than today’s computers.

The unconventional lens, which is 100 times thinner than a human hair, could enable a fast and reliable transfer of information from the new-age computers to a network, once these technologies are fully realised.

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Your body’s internal clock, or the circadian rhythm, regular when you sleep and wake, when you’re hungry, and when you’re most productive. Because of its effect on so much of our lives, it also has an enormous impact on our health, so sleep experts have designed a blood test to signal when your body is out of sync.

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We haven’t seen SpaceX’s BFR — the rocket that it hopes will enable trips around the world, to the Moon, and, eventually, to Mars — actually take flight yet, but the company says it has already booked a private passenger for a trip around the Moon. No one has been there since Apollo missions ended in the 70s, but now, in a “world’s first” SpaceX is apparently taking reservations. Details like who is going and “why” are to be revealed during a livestream on Monday September 17th at 9 PM ET.

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Research has shed new light on genetic processes that may one day lead to the development of therapies that can slow, or even reverse, how our cells age.

A study led by the University of Exeter Medical School has found that certain genes and pathways that regulate – a group of proteins in our body that tell our genes how to behave—play a key role in the ageing process. Significantly, the team found that disrupting these genetic processes could reverse signs of ageing in cells.

The study, published in the FASEB Journal, was conducted in human cells in laboratories. Aged, or senescent, cells are thought to represent a driver of the ageing process and other groups have shown that if such cells are removed in animal models, many features of ageing can be corrected. This new work from the Exeter team found that stopping the activity of the pathways ERK and AKT, which communicate signals from outside the cell to the genes, reduced the number of senescent cells in in cultures grown in the laboratory. Furthermore, they found the same effects from knocking out the activity of just two genes controlled by these pathways—FOX01 and ETV6.

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While blood stem cells from bone marrow have long been a cornerstone of treating blood cancers like leukemia and lymphoma, Mackenzie’s trial extracting the cells from a pregnant woman to treat a developing fetus in utero is just one of several innovative uses of stem cells to treat a growing list of diseases with cells instead of drugs. And promising studies are inching more of these stem-cell-based treatments closer to finally being tested in people.

With stem cells like those found in bone marrow, scientists are taking advantage of what the body does naturally: generate itself anew. Many of the adult body’s organs and tissues, including fat cells and blood, are equipped with their own stash of stem cells whose sole job is to regenerate cells and tissues when older ones are damaged or die off and which can be harvested for research and growth outside the body.

Some organs are not endowed with these large stem-cell reservoirs, however, most notably the brain and heart muscle. So more than two decades ago, scientists found another source of these flexible cells–in embryos that were donated for research from in vitro fertilization clinics. They learned how to grow these cells in the lab into any cells in the body. That opened the possibility that conditions like heart disease, diabetes or even psychiatric disorders might eventually be treated by replacing damaged tissues or organs with healthy ones, which could provide cures and treatments that didn’t require drugs or surgery.

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