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Discovery Provides Hope Of More Effective, Safer Cryopreservation

Cryogenics are an old science fiction dream, but today we still struggle to store large tissues without harming them. Now a breakthrough could lead to a safer, more reliable approach.

” This could be an important step toward the preservation of more complex tissues and structures”

Overcoming past challenges

Cryopreservation of biological material is commonplace, but there are remaining challenges. The initial problem with freezing any cell is crystallization, in which ice crystals form and rupture cells. This was overcome by using molecules like ethylene glycol, which essentially act like anti-freeze and prevent crystallization from happening. These are very effective, but they’re also often toxic; damaging or killing some cells in the process. This has made storage of larger tissues very challenging.

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