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Genes Responsible for Limb Regeneration in Crickets Identified

Posted in biotech/medical, genetics

Researchers just identified part of the epigenetic pathways responsible for limb regeneration in the two-spotted cricket Gryllus bimaculatus.

Cut off the leg of an insect, and not only will the insect survive, but the leg will also grow back after some time. Cut off the leg of a human, and they’ll bleed out without proper medical attention (alas for us). Ultimately, insects are able to accomplish this amazing feat because they retain the biological pathways required for cells to differentiate and reorganize at a wound site, which is required in order to regenerate entire limbs.

The processes involve the dedifferentiation and redifferentiation of cells; however, the exact nature of the process is largely a mystery. Fortunately, some light has recently been shed on the matter, as researchers at Okayama University identified key genes involved in the regenerative process of the two-spotted cricket, Gryllus bimaculatus.

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