Bone loss and frailty greatly diminish quality of life as we get older, and learning how to regrow bone across the body is a key rejuvenation target.
Stem cells are difficult to work with
We can now produce induced pluripotent stem cells from adult tissue, but differentiating them into a specific tissue is a major challenge. We’re still working on finding the exact chemical cues that create each specific cell type, and stem cells are highly sensitive. There has been progress in many areas, but we still have a way to go.