A 50-year-old science problem has been solved and could allow for dramatic changes in the fight against diseases, researchers say.
For years, scientists have been struggling with the problem of “protein folding” – mapping the three-dimensional shapes of the proteins that are responsible for diseases from cancer to Covid-19.
Google’s Deepmind claims to have created an artificially intelligent program called “AlphaFold” that is able to solve those problems in a matter of days.
Plant scientists have revolutionised science and innovation. Research around the cell or cell biology was born out of plant science.
Researching plants is vital for our food security, maintaining our ecosystems and in our fight against climate change. Plant science is equally important to generate new knowledge that breaks disciplinary barriers to revolutionise several fields of research and innovation. But despite its valuable contribution, scientists and prospective young scientists often overlook plant science. It’s because of this low recognition, plant science doesn’t get the same prestige as other disciplines. This is detrimental to the future of plant science as bright young students continue to choose a career away from plant science. I never considered studying plants myself — it was entirely accidental that I studied plant science.
In other words, scientists and prize committees question the influence of basic plant science across different disciplines.
But the fact is that ever since the early days of science, plants have been central to breakthroughs. Discoveries in plant science have enabled technological advances that we enjoy today. Therefore, I’m aiming to write a series of blog posts to highlight a few significant findings from research in plants. Here, I explain how plant research revolutionised the field of cell biology.
The United Arab Emirates’ first foray beyond Earth’s orbit is going so smoothly that the nation’s Hope Mars spacecraft will tackle some bonus observations before it reaches its destination, mission leaders have announced.
Although Drosophila is an insect whose genome has only about 14,000 genes, roughly half the human count, a remarkable number of these have very close counterparts in humans; some even occur in the same order in the fly’s DNA as in our own. This, plus the organism’s more than 100-year history in the lab, makes it one of the most important models for studying basic biology and disease.
To take full advantage of the opportunities offered by Drosophila, researchers need improved tools to manipulate the fly’s genes with precision, allowing them to introduce mutations to break genes, control their activity, label their protein products, or introduce other inherited genetic changes.
“We now have the genome sequences of lots of different animals — worms, flies, fish, mice, chimps, humans,” says Roger Hoskins of Berkeley Lab’s Life Sciences Division. “Now we want improved technologies for introducing precise changes into the genomes of lab animals; we want efficient genome engineering. Methods for doing this are very advanced in bacteria and yeast. Good methods for worms, flies, and mice have also been around for a long time, and improvements have come along fairly regularly. But with whole genome sequences in hand, the goals are becoming more ambitious.”
Host Mark Sackler and panelists discuss the challenges of getting governments and the public on board with one of the basic principles of longevity research: that the cause of all chronic diseases of aging is aging itself.
Last week, SpaceX has launched the Beta for its Starlink internet program. This space-based internet is turning out to be faster than expected, thus having the potential to give many people around the world opportunities to do things that their socio-economic situations would have never allowed them to have.
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Origami-inspired tissue engineering — using eggshells, plant leaves, marine sponges, and paper as substrates.
Ira Pastor ideaXme life sciences ambassador interviews Dr. Gulden Camci-Unal, Ph.D. Assistant Professor, at the Department Chemical Engineering, Francis College of Engineering, UMass Lowell.
Ira Pastor comments:
A few episodes ago ideaXme hosted the University of Michigan’s Dr. Bruce Carlson. We spoke to him about the interesting topic of the importance of “substrate” in regenerative processes, for both the maintenance of normal tissue functions, and in the migration of cells or changes to tissue architecture that are part of healing processes.
Substrate is broadly defined as the surface or material on, or from which, cells / tissues live, grow, or obtain nourishment, and have both biochemical, as well as biomechanical functions.
Today, on ideaXme to discuss some really fascinating, next generation work that is going on in this domain, we are joined Dr. Gulden Camci-Unal, Ph.D. Assistant Professor, Department Chemical Engineering, Francis College of Engineering, UMass Lowell.
Dr Camci-Unal received her Ph.D. in Chemistry at Iowa State University (USA) and her M.Sc. and B.Sc. degrees both in Chemical Engineering at Middle East Technical University (Turkey).
Dr. Camci-Unal’s research is at the interface of biomaterials and bioengineering, including the design, synthesis, and characterization of functional biomaterials for applications in tissue engineering and regenerative medicine, development of in vitro disease models for personalized medicine, as well as work in the area low-cost point of care diagnostics.