Lifeboat Foundation: Safeguarding Humanity
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Category: neuroscience

A landmark study has revealed that cholesterol in the brain may play a fundamental role in catalyzing the formation of amyloid beta clusters, thought to be a central mechanism leading to the devastating degenerative symptoms of Alzheimer’s disease.

An international team of researchers, led by the University of Cambridge, set out to uncover what causes amyloid beta proteins to cluster into the plaques that slowly accumulate and cause the primary degenerative symptoms of Alzheimer’s disease.

“The levels of amyloid-beta normally found in the brain are about a thousand times lower than we require to observe it aggregating in the laboratory – so what happens in the brain to make it aggregate?” asks Michele Vendruscolo, lead on the new research.

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Time to end genetic fatalism: Lifestyle matters, even to those with APOE e4 allele. #dementia #alzheimers #apoee4 #lifestyle #genetics

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A scientific experiment to reanimate dead brains could lead to humans enduring a ‘fate worse than death,’ an ethics lecturer has warned.

Last month Yale University announced it had successfully resurrected the brains of more than 100 slaughtered pigs and found that the cells were still healthy.

The reanimated brains were kept alive for up to 36 hours and scientists said the process, which should also work in primates, offered a new way to study intact organs in the lab.

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On a recent BBC World Service program (News Hour Extra, 12.18.15), a group of space scientists were gathered to discuss these and other aspects of the post-human era. “What about the human soul”, the moderator asked, wondering whether or not these post-humans would still be human. None of the participants were particularly troubled by the question, since they all had assumed that the soul was no more than the particular configurations of DNA which resulted in varying degre…es of insight, intelligence, creativity, and sensitivity. Post-humans will be no different, they all agreed. Only their individual genomes will have been altered to produce a very different human reality – in other words a different human soul.

Once the human genome was completely sequenced; once efforts to recombine DNA had become a reality; and once a mind-computer interface had been realized, there was never any doubt that a post-human era was coming.

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