Who isn’t interested in new ways to apply stem cell therapy these days?

Speaking of, have you heard about the scientists in Philadelphia, PA, who have been injecting stem cells directly into the spinal cords of medically brain-dead people in order to revive them?

In a page taken from Mary Shelley’s Frankenstein, the idea of “bringing people back from the dead” is a little too much like “playing God” for some critics to appreciate.

Open brain surgery is about as dangerous as it sounds, but for sufferers of conditions like Parkinson’s and epilepsy it can be the only way to relieve their symptoms. Unfortunately, this means drilling a hole in the skull and stimulating the brain with electrical currents, bringing on the risk of serious side effects. Fortunately, scientists have opened a new doorway to the brain, developing the Stentrode, a promising first-of-a-kind device that can deliver the currents to targeted areas through a small keyhole incision in the neck.

Scientists can now discover how the fine details of gene activity differ from one cell type to another in a tissue sample, thanks to a technique invented by Weill Cornell Medicine researchers.

The technique, described in a paper published Oct. 15 in Nature Biotechnology, will enable biologists to better understand the distinct molecular workings of different cell types in the body. It may also enable the improved understanding and treatment of diseases caused by abnormal gene activity.

“An individual gene can ‘say’ different things, and the true meaning often requires listening to entire phrases, rather than single words,” said senior study author Dr. Hagen U. Tilgner, assistant professor of neuroscience in the Feil Family Brain and Mind Research Institute at Weill Cornell Medicine. “Our new method essentially allows us to record complete phrases, called isoforms, that each gene expresses in each cell.”