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Here’s something you don’t hear every day: two theories of consciousness are about to face off in the scientific fight of the century.

Backed by top neuroscientist theorists of today, including Christof Koch, head of the formidable Allen Institute for Brain Research in Seattle, Washington, the fight hopes to put two rival ideas of consciousness to the test in a $20 million project. Briefly, volunteers will have their brain activity scanned while performing a series of cleverly-designed tasks targeted to suss out the brain’s physical origin of conscious thought. The first phase was launched this week at the Society for Neuroscience annual conference in Chicago, a brainy extravaganza that draws over 20,000 neuroscientists each year.

Both sides agree to make the fight as fair as possible: they’ll collaborate on the task design, pre-register their predictions on public ledgers, and if the data supports only one idea, the other acknowledges defeat.

The calls started pouring in soon after word spread that Dr. Valerie Taylor was testing fecal microbiota transplantation — transferring poop from one body to another — for bipolar disorder.

The mental health condition is different from depression. It comes with mania, the “up” swings that can make people feel superhuman. “But so many people with depression called wanting to take part in the study we felt we had an obligation to try,” said Taylor, chief of psychiatry at the University of Calgary.

Two years after spearheading the bipolar study, the first of its kind in the world, Taylor has now launched a second study testing fecal transplants in people with depression, as well as a third for depression in people who also have irritable bowel syndrome.

Correlations between pain phenotypes and psychiatric traits such as depression and the personality trait of neuroticism are not fully understood. In this study, we estimated the genetic correlations of eight pain phenotypes (defined by the UK Biobank, n = 151,922–226,683) with depressive symptoms, major depressive disorders and neuroticism using the cross-trait linkage disequilibrium score regression (LDSC) method integrated in the LD Hub. We also used the LDSC software to calculate the genetic correlations among pain phenotypes. All pain phenotypes, except hip pain and knee pain, had significant and positive genetic correlations with depressive symptoms, major depressive disorders and neuroticism. All pain phenotypes were heritable, with pain all over the body showing the highest heritability (h2 = 0.31, standard error = 0.072). Many pain phenotypes had positive and significant genetic correlations with each other indicating shared genetic mechanisms. Our results suggest that pain, neuroticism and depression share partially overlapping genetic risk factors.

Ira Pastor, ideaXme exponential health ambassador and founder of Bioquark, interviews Dr Wise Young M.D., Ph.D., the Richard H. Shindell Chair in Neuroscience, Distinguished Professor of Cell Biology & Neuroscience and the Founding Director of the W. M. Keck Center for Collaborative Neuroscience at Rutgers University.

If you enjoy this interview please donate to ideaXme here https://radioideaxme.com/contact/.

Spinal Cord Injury

A spinal cord injury (SCI) is defined as any damage to the spinal cord that causes temporary or permanent changes in its function.

Depending on the location and severity of the damage, the symptoms vary, from numbness to paralysis to incontinence. Long term outcomes also vary widely, from full recovery to permanent quadriplegia or paraplegia. Complications can include muscle atrophy, pressure sores, infections, and breathing problems.

Direct medical expenses for spinal cord injuries can run into millions of dollars (not including lost wages and earning potential) and can include: spinal surgery, trauma care (use of a ventilator) rehabilitation (including physical and occupational therapy, speech therapy, and mental health counseling), long-term care, including the costs of in-home aides, medical equipment such as wheelchairs, and medication such as painkillers and antibiotics.

https://www.youtube.com/watch?v=fhx1tf9VGiY&t=1s