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Category: nanotechnology

Could we eventually see a day where we have cell circuitry nanobot pill that eliminates hunger and obesity as replacement to gastric bypasses? Maybe.

The human body responds to starving conditions, such as famine, to promote the chance of survival. It reduces energy expenditure by stopping heat production and promotes feeding behavior. These “hunger responses” are activated by the feeling of hunger in the stomach and are controlled by neuropeptide Y (NPY) signals released by neurons in the hypothalamus. However, how NPY signaling in the hypothalamus elicits the hunger responses has remained unknown.

Sympathetic motor neurons in the medulla oblongata are responsible for heat production by brown adipose tissue (BAT). Researchers centered at Nagoya University have now tested whether the heat-producing neurons respond to the same hypothalamic NPY signals that control hunger responses. They injected NPY into the hypothalamus of rats and tested the effect on heat production. Under normal conditions, blocking inhibitory GABAergic receptors or stimulating excitatory glutamatergic receptors in the sympathetic motor neurons induced heat production in BAT. After NPY injection, stimulating glutamatergic receptors did not produce heat, but inhibiting GABAergic receptors did. The study was recently reported in Cell Metabolism.

Retrograde and anterograde tracing with fluorescent dyes revealed which brain region provided the inhibitory GABAergic inputs to heat-producing motor neurons.

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Today scientists at the Institute for Research in Biomedicine (IRB Barcelona) present a study in Cell (“The in vivo architecture of the exocyst provides structural basis for exocytosis”) where they have been able to observe protein nanomachines (also called protein complexes)—the structures responsible for performing cell functions—for the first time in living cells and in 3D. This work has been done in collaboration with researchers at the University of Geneva in Switzerland and the Centro Andaluz de Biología del Desarrollo in Seville.

3D observation of nanomachines in vivo

On the left, in vivo image of nanomachines using current microscopy techniques; on the right, the new method allows 3D observation of nanomachines in vivo and provides 25-fold improvement in precision (O. Gallego, IRB Barcelona)

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Advanced photonic nanostructures are well on their way to revolutionising quantum technology for quantum networks based on light. Researchers from the Niels Bohr Institute have now developed the first building blocks needed to construct complex quantum photonic circuits for quantum networks. This rapid development in quantum networks is highlighted in an article in the journal Nature.

Quantum technology based on light (photons) is called , while electronics is based on electrons. Photons (light particles) and electrons behave differently at the quantum level. A quantum entity is the smallest unit in the microscopic world. For example, photons are the fundamental constituent of light and electrons of electric current. Electrons are so-called fermions and can easily be isolated to conduct current one electron at a time. In contrast photons are bosons, which prefer to bunch together. But since information for quantum communication based on photonics is encoded in a single photon, it is necessary to emit and send them one at a time.

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The things that can be done with 3D printing never cease to amaze. To the casual observer with only a passing knowledge of the technology, it appears on the surface to be an interesting method of producing plastic odds and ends, and sometimes metal parts – but 3D printing is so much more, as anyone who follows the progression of the technology on a regular basis knows. The things it is capable of producing are often hard to wrap one’s mind around – especially when you look at 3D printing on the nanoscale.

A group of scientists from Lithuania, France and Australia are busy studying 3D printing on a very small scale. As a newly published paper entitled “Optically Clear and Resilient Free-Form μ-Optics 3D-Printed via Ultrafast Laser Lithography” explains, 3D printing is capable of creating functional objects that are impossible to produce via conventional manufacturing techniques, and structures at the miniature, micro- and nanoscales are no exception.

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Nice. I want one.

A revamped and rebranded NanoFabrication Kingston has launched with the goal of increasing activity outside of Queen’s University.

“We want to be open to the eastern Ontario community, industry and government as well as academia outside of Queen’s to make, characterize and test devices and samples that are small,” said Rob Knobel, Queen’s University professor and a lead researcher at NanoFabrication Kingston.

The lab’s basis is for the study and creation of innovations that require a scale of millionths of a millimetre.

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In Brief:

  • Predictions from the co-chair of the World Economic Forum’s Future Council, Melanie Walker, say we’ll soon enter a post-hospital world due to advances in personalized medicine, health monitoring, and nanotechnology.
  • New and evolving technologies in medical science convince Walker we’ll live in a society not dependent on hospitals by 2030.

As the world of medicine is increasingly changed by biology, technology, communications, genetics, and robotics, predicting the outlook of the next few decades of medicine becomes harder. But that is exactly what Melanie Walker of the World Economic Forum does, and she predicts a bright new future for healthcare.

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A simple technique for producing oxide nanowires directly from bulk materials could dramatically lower the cost of producing the one-dimensional (1D) nanostructures.

That could open the door for a broad range of uses in lightweight structural composites, advanced sensors, electronic devices – and thermally-stable and strong battery membranes able to withstand temperatures of more than 1,000 degrees Celsius.

The technique uses a solvent reaction with a bimetallic alloy – in which one of the metals is reactive – to form bundles of nanowires (nanofibers) upon reactive metal dissolution.

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