Lifeboat Foundation: Safeguarding Humanity
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Category: life extension

TODAY (Oct 4th) the USTP is holding a special pre-RAADFest Enlightenment Salon at 7 a.m. PST / 10 am EST with Gabor Kiss, CEO of ENVIENTA, to discuss ways to empower contributors to open-source projects and accelerate development of practical transhumanist technologies.

Ira Pastor, ideaXme life sciences ambassador, interviews Dr. Alexandre Kalache, President of the International Longevity Centre-Brazil (ILC-Brazil).

Ira Pastor Comments:

As we continue our virtual road-trip around the globe per the World Health Organization’s (WHO) Age Friendly Cities Global Movement, during the WHO defined “Decade of Healthy Aging”, we are headed down to the southern hemisphere to the country of Brazil.

Dr. Alexandre Kalache:

Dr. Alexandre Kalache is a medical epidemiologist specializing in the study of aging, who is the President of the International Longevity Centre-Brazil (ILC-Brazil), an independent think tank based in Rio de Janeiro that develops and promotes policy related to population aging, and Co-President of the Global Alliance of International Longevity Centres, an international consortium of member organizations with a mission to help societies to address longevity and population aging in positive and productive ways.

Dr. Kalache graduated from the medical school of the Federal University of Rio de Janeiro, gained diplomas in infectious and parasitic diseases and medical education, was awarded a master’s degree in Social Medicine from the London School of Hygiene and Tropical Medicine, his PhD in Epidemi ology at the University of London, and had a long academic career at the Universities of London and Oxford in the United Kingdom.

Dr. Kalache’s work in Aging:

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Founder of MakeLoveNotPorn, and internationally famous advertising executive and public speaker, talks of Sex-Tech, a burgeoning trillion dollar industry, on the ideaXme show — #Ideaxme #MoveTheHumanStoryForward #CindyGallop #MakeLoveNotPorn #SexTech #Sexuality #SociallyAcceptableSex #Pornography #Porn #Orgasm #ErectileDysfunction #Biohacking #Viagra #Wellness #Health #Longevity #DisruptAging #Aarp #IfWeRanTheWorld #BartleBogleHegarty #Advertising #PublicRelations #TEDTalk #IraPastor #Bioquark #Regenerage AARP Disrupt Aging.

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In the coming 2020s, the world of medical science will make some significant breakthroughs. Through brain implants, we will have the capability to restore lost memories.

~ The 2020s will provide us with the computer power to make the first complete human brain simulation. Exponential growth in computation and data will make it possible to form accurate models of every part of the human brain and its 100 billion neurons.

~ The prototype of the human heart was 3D printed in 2019. By the mid- 2020s, customized 3D- printing of major human body organs will become possible. In the coming decades, more and more of the 78 organs in the human body will become printable.

…As we enter into the next few decades, we will have the technologies that grant us the possibility of immortality, albeit one that is highly subjective.

With our ability to 3D print new body organs, our ability to use nanotechnology in fighting death at cellular levels, our ability to use CRISPR or other gene-editing technology to rewrite our definition of humans and even our ability to capture and extend our consciousness beyond the confines of the biological weakness of our human bodies — immortality may be within reach of our fingers as depicted in the painting of Michelangelo.

The race to human 2.0 will be run broadly in two spectrums — the evolution of our body and the evolution of our minds.

Excerpt from my book — 2020s & The Future Beyond.

#Future #Humanity #Transhumanism

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Every human being is home to trillions of microbes that are collectively known as the microbiota. Recent research into how these microbes affect the immune system may explain why older people are more vulnerable to disease and suggest ways to tackle that vulnerability.

Scientists at The University of Edinburgh’s Roslin Institute, led by Professor Neil Mabbott, discovered that as mice get older they showed a marked decrease in the number of M cells found in the lining of the gut. These are specialised cells that look out for infections and trigger the early stages of the immune response. Fewer M cells means a weaker immune system. At the same time, the researchers found that the older mice had depleted microbiota compared to younger mice. The microbiota were less diverse and certain species known to decrease inflammation of the gut in humans were missing.

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Fecal transplants could one day be used as a therapy to restore cognitive function in the elderly—according to new research from the University of East Anglia, the University of Florence and the Quadram Institute.

A new study published today shows how fecal transplants from older to younger mice altered their , which in turn impacted their spatial learning and memory.

The research team hope that reversing the procedure could one day see fecal transplantation used to combat cognitive decline among the elderly.

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Beyond 2030 with Gennady Stolyarov II of the United States Transhumanist Party: Growing a Mainstream Transhumanist Movement In “2030: Beyond the Film” Direct…Gennady Stolyarov II: Growing a Mainstream Transhumanist Movement.

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Transdisciplinary Agora for Future Discussions (TAFFD’s) is a global nongovernmental organization registered in the USA that serves as a futuristic think tank endeavored to the education and engagement urgency to help people understand the benefits and challenges of technology applied to high-impact industries and disciplines across the world.

We help prepare people’s minds by talking about the current advantages of this new paradigm and what the future entails using a trans-disciplinary approach that is transposed through the TAFFD’s Quarterly Journal, TAFFD’s annual Magazine, TAFFD’s International/Local Conferencing, TAFFD’s Awards, and TAFFD’s Teens divisions of our organization.

TAFFD’s is grateful & honored to be supported/endorsed by the Lifeboat Foundation, USTP, International Longevity Alliance, Open Source Mode, Emerge, Aubrey de Grey, Catherine Demetriades and by many people who wish to change the world through the proper use of technology.

JOIN US!
https://www.taffds.org

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LEAF president Keith Comito explains the story of Lifespan.io — a crowdsourcing platform and community to support biomedical research aimed at extending healthy human lifespan.
▼▼ More info and links below ▼▼

HOW CAN YOU SUPPORT US?
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LEAF / Lifespan.io is a 501©(3) nonprofit organization. Everything we’ve done thus far and everything we will do in the future is thanks to your support — please stand with us to fight the diseases of aging and increase healthy human lifespan.

► Support us with monthly donations by becoming a Lifespan Hero: https://www.lifespan.io/hero
► Make a one-time donation and learn about other ways to support us here: http://lifespan.io/support
► Learn more, and help us #CrowdsourceTheCure: https://www.lifespan.io
► Subscribe: http://www.youtube.com/user/LifespanIO?sub_confirmation=1

THANKS TO THE SUPPORT OF PEOPLE LIKE YOU, WE HAVE:
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► Crowdfunded over $400,000 for credible research projects addressing the root causes of aging
► Worked with amazing channels like @Kurzgesagt – In a Nutshell and @Life Noggin on videos to inform and engage the public in our work.
► Built up the most trafficked news outlet and online community on the subject of aging research, with over 150,000 members across various platforms and social media: https://www.lifespan.io/news
► Created a monthly livestreamed Journal Club to explain the latest research to you in real time: https://www.lifespan.io/journalclub
► Began to host our flagship Ending Age-Related Diseases annual conference in New York City, bringing together researchers, investors, regulators, press, and the public: https://www.lifespan.io/conference
► Created the premier network of investors focused on supporting this work, the Longevity Investor Network, which holds monthly pitch meetings to review the most promising and credible up-and-coming companies in the field: https://www.lifespan.io/investor
► Built powerful online tools, such as our Rejuvenation Roadmap, which shows you at glance the latest updates in the field: https://www.lifespan.io/roadmap
► Began to create educational video content, such as our LifeXtenShow: https://www.lifespan.io/x10

NEWS & SOCIAL MEDIA
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News: https://www.lifespan.io/news
Facebook: https://www.lifespan.io/facebook
Instagram: https://www.lifespan.io/instagram
LinkedIn: https://www.lifespan.io/linkedin
Twitter: https://www.lifespan.io/twitter
Discord: https://www.lifespan.io/discord
Newsletter: https://www.lifespan.io/newsletter

YOUTUBE COLLABORATIONS:
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Kurzgesagt: https://www.youtube.com/watch?v=MjdpR-TY6QU
Life Noggin: https://www.youtube.com/watch?v=EEO4bHbxRgo

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In a study of gorilla skeletons collected in the wild, Johns Hopkins Medicine researchers and their international collaborators report that aging female gorillas do not experience the accelerated bone loss associated with the bone-weakening condition called osteoporosis, as their human counterparts often do. The findings, they say, could offer clues as to how humans evolved with age-related diseases.

The study was published on Sept. 21, 2020, in Philosophical Translations of the Royal Society B.

“Osteoporosis in humans is a really interesting mechanical problem,” says Christopher Ruff, Ph.D., professor at the Center for Functional Anatomy and Evolution at the Johns Hopkins University School of Medicine. “In terms of natural selection, there is no evolutionary advantage in developing with aging to the point of a potential fracture. By looking at close relatives of humans on the evolutionary tree, we can infer more about the origins of this condition.”

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The number of mutations that can contribute to aging may be significantly higher than previously believed, according to new research on fruit flies. The study by scientists at Linköping University, Sweden, supports a new theory about the type of mutation that can lie behind aging. The results have been published in BMC Biology.

We live, we age and we die. Many functions of our bodies deteriorate slowly but surely as we age, and eventually an organism dies. This thought may not be very encouraging, but most of us have probably accepted that this is the fate of all living creatures—death is part of life. However, those who study find it far from clear why this is the case.

“The evolution of aging is, in a manner of speaking, a paradox. Evolution causes continuous adaptation in organisms, but even so it has not resulted in them ceasing to age,” says Urban Friberg, senior lecturer in the Department of Physics, Chemistry and Biology at Linköping University and leader of the study.

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Not too much here, but longevity research fans might like.

Time may be our worst enemy, and aging its most powerful weapon. Our hair turns gray, our strength wanes, and a slew of age-related diseases represent what is happening at the cellular and molecular levels. Aging affects all the cells in our body’s different tissues, and understanding its impact would be of great value in fighting this eternal enemy of all ephemeral life forms.

The key is to first observe and measure. In a paper published in Cell Reports, scientists led by Johan Auwerx at EPFL started by asking a simple question: how do the tissues of aging mice differ from those of mice that are mere adults?

To answer the question, the researchers used the multiple techniques to measure the expression of everyone one of the thousands of mouse’s genes, and to identify any underlying epigenetic differences. The researchers not only measured different layers of information, but they did it across three different tissues: liver, heart, and muscle.

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