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A new article on my campaign with a provocative headline, but most of the story is nice. I’ll be speaking in Florida on Saturday as part of the Immortality Bus tour. We visited Alabama’s largest megachurch yesterday:


His name sounds funny to Americans, but presidential candidate Zoltan Istvan says it’s totally normal in Hungary, from where his parents hail. Istvan himself was born in Los Angeles and worked for National Geographic for years — a job that led him to explore science, particularly the concept of transhumanism, which posits that people will merge with technology.

Today, Istvan continues to write for Vice, Psychology Today, Gizmod o, and more — when he’s not campaigning across the country and promoting the Transhumanist Party platform, which promises better lives — and hopefully immortality — through science. Istvan will speak this Saturday at the Church of Perpetual Life in Hollywood, which promotes the same ideals and which New Times featured in a cover story earlier this year.

Istvan says that as a journalist, he used to cover nature, until “we were in Vietnam and I had a very close call with a land mine. I thought, ‘Why don’t I write less about nature and the environment and more about science, medicine, and future uses of science to conquer death?’” After leaving Nat Geo circa 2004, when he was about 28, to take care of his ailing father, he says he made some money in real estate and in 2013, “I wrote a novel called The Transhumanist Wage r, which launched my career as a futurist.”

Now he’s onboard with the Transhumanist Party, which has been established for about 14 months, he says. “It’s an actual, organized national party,” he says, though you’re unlikely to see it on a ballot because it’s nearly impossible for small political parties to get on “unless you have almost 50 or 60 million dollars lying around.”

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Researchers at the Salk Institute working on an experimental Alzheimer’s drug have discovered it may have a host of anti-aging effects too.

Building on previous work

Research had already been conducted on the drug candidate, J147, with the aim of targeting Alzheimer’s. The results showed the drug could help prevent and even regenerate; reversing memory loss and a form of inherited Alzheimer’s disease in mice subjects. While this form comprises only 1% of Alzheimer’s cases, the biggest risk factor for the remainder is old age. If you could target brain aging itself, risk factors would be significantly reduced.

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Resetting Your Biological Clock: New Enzyme Found To Repair Telomeres.

The telomere caps on the end of your chromosomes unravel bit by bit with every cell division, and if they’re not repaired division eventually stops altogether. Cells like stem cells express special enzymes to lengthen these caps, and we’ve now found another one that does the job.

A key player in aging?

Many factors drive aging, but telomeres play a key role in allowing cells to divide at all and are therefore a major potential anti-aging target. Aging is a murder mystery case involving a range of perpetrators, but telomere shortening has been connected to multiple age-related diseases and many scientists believe we’ll have to find ways to repair telomeres if we want to live longer.

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I had read about Singapore in genetic engineering way back in the 90’s. I think they were 1st or 2nd in making immortal skin cells at the time.


Singapore scientists have unravelled a mystery that could pave the way for turning back the clock on ageing.

A recent study led by Dr Ng Shyh Chang of the Genome Institute of Singapore at the Agency for Science, Technology and Research (A*Star) has found a gene in human egg cells that suppresses an enzyme causing cells to age.

This is the Tcl1 gene, and by increasing the protein it produces, the researchers found they could suppress the enzyme that causes mitochondria — the cells’ batteries — to age over time.

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New article for Vice Motherboard on why society should support legalization of all drugs–and a short video of the Immortality Bus in Arkansas talking to marijuana supporters (a state where it’s totally illegal):


The “Mount Rushmore of the Drug War” featuring founding prohibitionists Harry Anslinger, Billie Holiday, and Arnold Rothstein. Image: Donkey Hotey/Flickr

I’m from San Francisco. Doing drugs—especially smoking pot—seems second nature to me. I’ve made a point of trying nearly all drugs, and I’m unabashedly proud of that fact. I consider Aldous Huxley’s The Doors of Perception one of the most important books I read in my youth, and I’ve often wondered if it should be mandatory that everyone try a hallucinogenic drug at least once in their lives.

Almost all transhumanists welcome and endorse mind-altering substances. We thrive off change, experimentation, and new experiences, including wild drug trips with friends. For transhumanists, trying drugs is not just about having fun, but about self-amelioration and becoming the best, most enlightened versions of ourselves.

I’m driving a bus across the country to deliver a Transhumanist Bill of Rights to the US Capitol. One of those rights will certainly include language that advocates for citizens being able to take any drugs they want, so long as the taking of it doesn’t directly hurt someone else.

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Might be a good start point for some new longevity research.


A new genetic analysis of human gut bacteria is turning up some really weird critters—so weird, in fact, that some biologists are speculating we’ve found an entirely new domain of life. We should take that possibility with a healthy dose of skepticism. But here’s why it’s even being discussed.

In the past ten years, new genomic technologies have, for the first time, enabled scientists to explore our microbiome—that trove of invisible critters that live on us and in us. Microbiome research is quite literally rewriting the textbooks on human biology, as we learn that everything from our mouths to our intestines to our skin is, in fact a complex and diverse ecosystem. Hell, we’re even surrounded in a personal cloud of bacteria. By some estimates, the human cells in your body are vastly outnumbered by microbes.

Now that we’ve come to appreciate just how ubiquitous our microbial tenants are, we’re starting to drill deeper and learn their identities. And that’s led to some surprises. For one, a lot of the bugs living in our gut are totally distinct from anything we’ve encountered before.

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Gooooood, good.


Big data will help crack the code on aging.

Two of the leading scientists at the edge of the medical revolution believe that our life expectancy could start creeping up toward the triple digits.

David Agus, a professor of medicine and engineering at the University of Southern California, said at the Fortune Global Forum on Monday that he believes that with our current technology humans have the potential to regularly live into their ninth or tenth decade.

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