“Sirtuins are kind of like an orchestra working together to produce a symphony, but each piece, each section, has its own role. Together you get a unified outcome, which we think is improved health.”
— Dr. Leonard Guarente
Dr. Leonard Guarente’s office in the Massachusetts Institute of Technology’s Koch Biology Building is, at first glance, a modest room filled with the artifacts of a decades-long career as a professor and researcher: archives of important journals including Cell, Molecular and Cellular Biology, and Nature; framed covers of his most important papers (he’s published more than 250); achievement awards recognizing his work in genetics and molecular biology; photos of his family; and odds and ends like a dagger presented to him by a student from Thailand and a faded bottle of The Macallan single malt scotch from 1980.
Staff members who die will be put in cold storage until medical science can revive them.
Since congressional Republicans voted in a bill containing the Trump administration’s roll back of the Affordable Care Act, healthcare is once again a topic on everyone’s lips. In the absence of any universal healthcare scheme, employer-provided medical coverage is a crucial benefit for employees, tempting people to stay at jobs they might otherwise have left, or apply for positions they wouldn’t otherwise consider.
In the contest to attract new hires, tech companies often supplement already generous salaries with comprehensive benefit packages, and in this vein one company has hit on a novel idea: A health plan that covers its employees beyond death and into the realms of a speculative future rebirth.
On May 16-19th a longevity research conference is being held in Paris.
On May 16-19th renowned researchers and advocates of healthy life extension will gather in Paris to discuss recent breakthroughs in regenerative medicine. The conference organized by the International Cell Senescence Association (ICSA) “The Ins and Outs of Cellular Senescence: Understanding the Biology to Foster Healthy Aging and Suppression of Disease” will take place in the famous Pasteur Institute in Paris. In addition to the main conference, an open public event will be held on the afternoon of May, 19th: an international panel of experts in aging research under the lead of Eric Gilson (Ircan research institute on cancer and aging in Nice) will reveal what we know about biological aging today and what medicine can do to prevent age-related diseases.
The main event will feature the latest cutting-edge findings in cell senescence – one of this year’s hottest topics in aging research with a host of guest speakers and discussions taking place over the four days. It will also explore recent findings such as the fact that some kinds of senescent cell appear to have positive effects like suppressing tumour development, or helping with regenerating tissues or wound healing – but seem to be different from those that accumulate in the body damaging health.
You can see how deep-rooted is the wish of some to just ignore the problem of ageing when they say that rejuvenation won’t happen in time for them, and that there’s thus no reason they should concern themselves with the whole issue. This article on rebuts this meta-objection and discusses its origins.
People’s last line of defence to keep ignoring the problem of ageing and rejuvenation is often the meta-objection ‘it won’t happen in my lifetime’. Let’s have a look at what’s wrong with this reasoning, and why some people think this way.
#aging #crowdfundthecure
https://rejuvenaction.wordpress.com/answers-to-objections/objections-to-rejuvenation/rejuvenation-wont-happen-within-my-lifetime/
The major mouse testing pogram is organizing a special 1.5 hour long longevity panel with Dr. Alexandra Stolzing, Dr. Aubrey de Grey and other guests in early June. This was one of the rewards for their campaign on Lifespan.io last year.
They are asking the community to suggest questions to ask Dr. Stolzing and Dr. de Grey so head on over there if you would like to ask them something and maybe it will make the show. The show will be broadcast live on Facebook and the dates will be announced shortly.
We hope to lifestream the science panel to facebook in June and will confirm the time and date shortly.
The longevity panel was one of the rewards for donating to our fundraiser last year on Lifespan.io and we are very excited about bringing this to our supporters soon.
We are taking suggestions for questions for the panelists now so if you have a question for Aubrey de Grey or Alexandra Stolzing about their work please let us know here.
https://www.youtube.com/watch?v=B-6-T_StYM8
From 2014, a docu focusing on Aubrey and Bill Andrews.
Live forever… or die trying
For downloads and more information visit: http://www.journeyman.tv/67791/documentaries/the-immortalists-hd.html
What would the world look like if humans never grew old? Two eccentric biologists are determined to find out. In this larger-than-life doc, Bill Andrews and Aubrey de Grey leave behind the journals and peer reviews of the scientific establishment to embark on a quest for the age-old secret of eternal youth. Can it be done? And is it desirable? They differ in their approach, but are united in their goal: to learn to live forever, or die trying.
Structure Films — Ref 6258
Every week Journeyman offers a brand new documentary, fresh out of the cutting room. They’re award winning documentaries, some destined for the festival circuit and some for broadcast. The one thing you can know is that here you get to see them when they’re fresh, often before they appear anywhere else. To watch them in full go to our VOD platform at http://jman.TV
What are the bottlenecks in developing a rejuvenation biotechnology industry? LEAF takes a look at some of the main problems we are facing in creating that industry.
One of the most frequent questions we get from the general public is when will rejuvenation therapies arrive? Whilst young people can wait for a few more decades, those in middle age are much more concerned. According to statistics, new drug development takes 17 years on average, but the countdown only begins at the moment when the underlying mechanisms are investigated well enough – which cannot be said about the mechanisms of aging.
We have made great progress in understanding aging in the last decade thanks to the march of technology. One solution to an aging process is entering human clinical trials this year: a therapy to remove aged damaged cells to promote tissue repair and reduce chronic inflammation. This is of course fantastic news but progress is still too slow.
So what is holding back the pace of the research on aging and what we can do to foster progress?
Research on aging began a long time ago. Back in 1900s the pioneer immunologist Elie Metchnikoff, vice-president of Pasteur Institute in Paris, wrote: “Aging is a disease and it should be treated like any other”. His work helped to shape interest in aging as a manageable problem. The first attempts to extend healthy life in animals by evidence-based medical means were undertaken in the middle of the 20th century. The most remarkable progress however has been made in the last 20 years, when the field of genetics finally blossomed. But the solutions that might prevent or significantly postpone age-related diseases are not available yet. Some might think it was a conspiracy, but there is actually a much more simple explanation: there are many factors that are holding back progress.
