Lifeboat Foundation: Safeguarding Humanity
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Category: life extension

Circa 1998

CELL BIOLOGY
F or cells, aging and cancer are often opposite sides of a genetic coin: With “heads,” cells will eventually stop dividing, reaching a permanently quiescent stage called senescence, as do normal human cells in lab cultures. With “tails,” the cells with genetic defects can become immortal and never stop dividing—a common characteristic of cultured cancer cells. Now, a group at Baylor College of Medicine in Houston has found a gene that may help determine which side the coin lands on.

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In an article last May, we covered how Rejuvenate Bio, a startup biotech company led by Professor George Church, was planning to reverse aging in dogs as a step towards bringing these therapies to us. Those plans are now starting to move forward with news of a trial launch in the fall later this year.

Developing anti-aging therapies in dogs is the first step

Back in 2015, the Church lab at Harvard began testing a variety of therapies focused on age reversal using CRISPR, a gene editing system that was much easier and faster to use than older techniques. Since then, Professor Church and his lab have conducted a myriad of experiments and gathered lots of data with which to plan future strategies for tackling aging.

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Announces the publication of a new 315-page open-access report: “National Longevity Development Plans: Global Overview 2019 (First Edition)”.

It offers comprehensive profiles of relevant initiatives in the UK, the Netherlands, Singapore, South Korea, Israel, Switzerland, Hong Kong, Japan, the USA, Spain, the European Union and China, and utilizes sophisticated analytical metrics to compare the overall strength, focus, proactivity and relevance of their Longevity-related projects, initiatives and development plans.

Link to the Report: https://www.aginganalytics.com/longevity-development-plans

#aging #ageing #longevity #ageingpopulation #demographicageing #aginganalytics #geroscience #governmentlongevity #industrialstrategy

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The latest SpaceX Dragon cargo mission to the International Space Station (ISS) included an experiment that could help to combat the ravages of time here on Earth. The European experiment will test how ceramic nanoparticles interact with cells to act as an anti-aging supplement that not only holds promise for alleviating the effects of growing old, but also for combatting chronic illness and space-related stresses for astronauts on prolonged space missions.

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AM I Wrong for wondering about Metformin and its true benefits against the Senesonic-Sensonic pandemic Plague mankind has called aging??? Metformin has been in use truly since the 1920’s and we have not found today an elderly person who is living 125 or 150 years who states they merely took metformin for diabetes??? Now Met has proven itself as a resistant against diabetes due to preventing the liver from making to much glucose that then enters the body. But is it a Longevity drug for mankind is the burning question??? You be the Judge… {I found this link on Antonei Benjamin Csoka group page on the book of faces} Respect r.p.berry & AEWR wherein we have found the causes and a cure for the Pandemic plague mankind has called aging… https://we search for partners and investors to join us in agings end…

Does it make sense to treat ageing as a disease?


Stem cell transplants have been of great interest to aging researchers, and, in a new study, they have successfully increased mouse lifespan by using stem cell therapy. While this has been previously achieved, this experiment was more refined than older studies and sheds new light on the potential of tissue regeneration through stem cells.

The significant extension of maximum lifespan could be considered an indication that any intervention is targeting a core hallmark of aging or, in the case of small increases of lifespan, at least indirectly influencing it.

Through bone marrow transplants, the researchers have significantly increased the lifespans of mice and believe that they are directly targeting an aging process directly [1]. Given that stem cell exhaustion is a hallmark of aging, they are likely correct.

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