Lifeboat Foundation: Safeguarding Humanity
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Category: life extension

Getting old is an unavoidable truth of life. And yet, for most of modern history this mortal coil has baffled scientists. Over the past decade, however, researchers have made great strides in understanding the cellular, molecular, and genetic tableau of aging—which has brought the next question into sharp focus: Can aging be stopped? While a full answer remains elusive, recent advancements have opened the door for significantly extending the human lifespan. One controversial researcher even claims that the first person who will live 1,000 years has already been born. Mainstream researchers are decidedly more cautious in their predictions, but the prospect of postponing mortality, even in modest ways, raises important ethical, social, and practical questions. How would we control an increasingly out-of-control global population? Does life have meaning without death? Even if we could live forever, would we want to?

The World Science Festival gathers great minds in science and the arts to produce live and digital content that allows a broad general audience to engage with scientific discoveries. Our mission is to cultivate a general public informed by science, inspired by its wonder, convinced of its value, and prepared to engage with its implications for the future.

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Original Program Date: June 2, 2011
MODERATOR: Bill Ritter
PARTICIPANTS: Leonard Guarente, Judith Campisi, Michael Rose, Aubrey de Grey.

Bill Ritter’s Introduction 0:05

Does Life Have Meaning Without Death? 02:50.

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Ira Pastor, ideaXme longevity and aging ambassador and founder of Bioquark, interviews James Strole, Co-Founder and Co-Director of People Unlimited and Director of the Coalition For Radical Life Extension.

Ira Pastor Comments:

On the last several shows we have spent time on different hierarchical levels the biologic-architecture of the life, disease and aging process. We’ve spent some time talking about the genome, the microbiome, tissue engineering, systems biology, quantum biology, organism hydrodynamics, biosemiotics, and chronobiology.

As exciting and promising as all of these research paths are, at the end of the day, in order for them to yield what many of us are looking for, radically extended healthspans and lifespans, and for them to be translated at scale, that is: approved by regulators, marketed by large pharma and CPG companies, and prescribed by a millions of clinicians (especially as the target market is all 7+ billion inhabitants of the planet), there needs to be an appropriate system of advocacy, education, awareness, and networking built around them to spread the word of the possibilities and the beautiful future that they can bring.

For today’s guest, I could think of no one better to come talk with us about this topic and take us into the future, than James Strole.

James is the Co-Founder and Co-Director of People Unlimited, an organization that’s involved in inspiring, educating, and connecting like minded people interested in achieving unlimited lifespans.

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A small clinical trial, which was conducted by a team of researchers led by Dr. Greg Fahy, has shown for the first time in humans that reversing biological age may be possible.

The results of TRIIM are in

The researchers spent a year running the Thymus Regeneration, Immunorestoration, and Insulin Mitigation (TRIIM) trial, which included 9 volunteers aged between 51 and 65. The trial was aimed at testing if a growth hormone and drug combination could be used safely in humans to restore thymic function lost due to aging [1].

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https://www.youtube.com/watch?v=xxILxijmub4

A 5 year study. In recent years it has been shown to extend the lives of nematodes (or roundworms) by 57% and mice by 6%. In humans, claims abound that metformin-takers are living longer, having fewer cardiovascular episodes and seeing reduced odds of getting cancer.

Groundbreaking TAME trial, which directly targets aging as an endpoint, finally begins this November, reveals lead clinician Dr Nir Barzilai.

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NBC is developing an untitled cryonics-themed project which hails from writer and executive producer David Slack and filmmaker Phillip Noyce who will direct the pilot and executive produce.

Sony Television produces the series which follows an enigmatic billionaire who has gathered more than 250 people who attempt to cheat death by undergoing cryogenic suspension in hopes that a future breakthrough would someday allow them to be brought back to life.

However, as these people from different moments in time wake up, they soon realise you can’t cheat death without paying a price. Josh Berman and Chris King will also serve as executive producer. Noyce also helmed the pilots of and executive produced ABC’s “Revenge” and FOX’s “The Resident”.

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