Lifeboat Foundation: Safeguarding Humanity
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Category: health

At least five downtown Denver hotels have closed temporarily to stem the coronavirus spread, and the statewide industry is bracing for a hit that could lead to as many as 72,000 job losses in a sector that produces a $13.4 billion annual gross domestic product statewide.

While only a handful of mountain resorts had shut down by early this week, that number has ballooned in recent days as hotels across the metro region are reporting vacancy levels below 10% during a month many had predicted would be record-setting, Colorado Hotel and Lodging Association President/CEO Amie Mayhew said. Among those that have announced they will shutter until May 11 or 12 are the Grand Hyatt Denver, the Oxford Hotel, the Crawford Hotel and The Maven Hotel at Dairy Block.

All of those except for the Grand Hyatt are operated by Sage Hospitality Group of Denver, whose CEO, Walter Isenberg, issued a letter Thursday saying he’d made “the very difficult decision to temporarily suspend business operations at a portion of our hotels and restaurants in order to protect the health and safety of our guests, our associates and our communities.”

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Dr. Ezekiel Emanuel, an American oncologist and bioethicist who is senior fellow at the Center for American Progress as well as Vice Provost for Global Initiatives at the University of Pennsylvania and chair of the Department of Medical Ethics and Health Policy, said on MSNBC on Friday, March 20, that Tesla and SpaceX CEO Elon Musk told him it would probably take 8–10 weeks to get ventilator production started at his factories (he’s working on this at Tesla and SpaceX).

I reached out to Musk for clarification on that topic and he replied that, “We have 250k N95 masks. Aiming to start distributing those to hospitals tomorrow night. Should have over 1000 ventilators by next week.” With medical supplies such as these being one of the biggest bottlenecks and challenges at the moment in the COVID-19 response in the United States (as well as elsewhere) — something that is already having a very real effect on medical professionals and patient care — the support will surely be received with much gratitude. That said, while there has been much attention put on the expected future need for ventilators, very few places reportedly have a shortage of them right now. In much greater need at the moment are simpler supplies like N95 masks, which must be why Tesla/SpaceX is providing 250,000 of them.

Dr. Emanuel also said in the segment of MSNBC’s “Morning Joe” he was on that we probably need 8–12 weeks (2–3 months) of social distancing in the US in order to deal with COVID-19 as a society. However, he also expects that the virus will come back and we’ll basically have a roller coaster of “social restrictions, easing up, social restrictions, easing up … to try to smooth out the demand on the health care system.”

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“Infusions of antibody-laden blood have been used with reported success in prior outbreaks, including the SARS epidemic and the 1918 flu pandemic.”

John Hopkins University

With a vaccine for COVID-19 still a long way from being realized, Johns Hopkins immunologist Arturo Casadevall is working to revive a century-old blood-derived treatment for use in the United States in hopes of slowing the spread of the disease.

With the right pieces in place, the treatment could be set up at Johns Hopkins University in Baltimore within a matter of weeks, Casadevall says.

The technique uses antibodies from the blood plasma or serum of people who have recovered from COVID-19 infection to boost the immunity of newly infected patients and those at risk of contracting the disease. These antibodies contained in the blood’s serum have the ability to bind to and neutralize SARS-CoV-2, the virus that causes COVID-19. Casadevall—a Bloomberg Distinguished Professor of molecular microbiology and immunology and infectious diseases at the Johns Hopkins Bloomberg School of Public Health and School of Medicine—published a paper on the proposal today in The Journal of Clinical Investigation.

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Bulky, buzzing and beeping hospital rooms demonstrate that monitoring a patient’s health status is an invasive and uncomfortable process, at best, and a dangerous process, at worst. Penn State researchers want to change that and make biosensors that could make health monitoring less bulky, more accurate—and much safer.

The key would be making sensors that are so stretchable and flexible that they can easily integrate with the human body’s complex, changing contours, said Larry Cheng, the Dorothy Quiggle Professor in Engineering and an affiliate of the Institute for Computational and Data Sciences. His lab is making progress on designing sensors that can do just that.

If biosensors that are both efficient and stretchable can be achieved at scale, the researchers suggest that engineers can pursue—and, in some cases, are already pursuing—a range of options for sensors that can be worn on the body, or even placed inside the body. The payoff would be smarter, more effective and more personalized medical treatment and improved health decision-making—without a lot of bulky, buzzing and beeping pieces of monitoring equipment.

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As of 29 February 2020 there were 79,394 confirmed cases and 2,838 deaths from COVID-19 in mainland China. Of these, 48,557 cases and 2,169 deaths occurred in the epicenter, Wuhan. A key public health priority during the emergence of a novel pathogen is estimating clinical severity, which requires properly adjusting for the case ascertainment rate and the delay between symptoms onset and death. Using public and published information, we estimate that the overall symptomatic case fatality risk (the probability of dying after developing symptoms) of COVID-19 in Wuhan was 1.4% (0.9–2.1%), which is substantially lower than both the corresponding crude or naïve confirmed case fatality risk (2,169/48,557 = 4.5%) and the approximator1 of deaths/deaths + recoveries (2,169/2,169 + 17,572 = 11%) as of 29 February 2020. Compared to those aged 30–59 years, those aged below 30 and above 59 years were 0.6 (0.3–1.1) and 5.1 (4.2–6.1) times more likely to die after developing symptoms. The risk of symptomatic infection increased with age (for example, at ~4% per year among adults aged 30–60 years).

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This Is-Real!!! Israeli pharmaceutical company, Teva, has announced that they will donate more than 6 million tablets through wholesalers to hospitals across the United States, from March 31.

As the coronavirus is spreading across the world, and the number of people infected is increasing everyday, there is an urgent need to find treatments against COVID-19 that could reduce complications and improve recovery. Recently, the Israeli Health Ministry has approved multiple experiment treatments, and companies worldwide are attempting to determine what could be used to treat COVID-19.

As such, Israeli pharmaceutical company, Teva, has announced that they will donate more than 6 million doses of hydroxychloroquine sulfate tablets through wholesalers to hospitals across the United States, from March 31. Over 10 million tablets are expected to be shipped within a month.

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In addition to working with the World Health Organization to end smallpox, Larry Brilliant has fought flu, polio, and blindness. He says we will, eventually, get back to normal. But that’s not going to occur until three important things happen first. LARRY BRILLIANT SAYS he doesn’t have a crystal ball. But 14 years ago, Brilliant, the epidemiologist who helped eradicate smallpox, spoke to a TED audience and described what the next pandemic would look like. At the time, it sounded almost too horrible to take seriously. “A billion people would get sick,” he said. “As many as 165 million people would die. There would be a global recession and depression, and the cost to our economy of $1 to $3 trillion would be far worse for everyone than merely 100 million people dying, because so many more people would lose their jobs and their health care benefits, that the consequences are almost unthinkable.”

Epidemiologist Larry Brilliant, who warned of pandemic in 2006, says we can beat the novel coronavirus—but first, we need lots more testing.

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ZURICH (Reuters) — Switzerland’s health care system could collapse by the end of the month if the new coronavirus keeps spreading at current rates, a government official warned on Tuesday.

Swiss authorities estimated that 2,650 people had tested positive for the coronavirus and said 19 people had died, while predicting cases will likely soar in the weeks ahead.

Exact figures were unavailable. Daniel Koch, head of the Federal Office of Health’s communicable diseases division, said the rapid rise had outstripped the state’s ability to record new cases in real time.

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