Lifeboat Foundation: Safeguarding Humanity
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Category: genetics

“According to many industry observers, we are today on the cusp of a Fourth Industrial Revolution. Developments in previously disjointed fields such as artificial intelligence and machine learning, robotics, nanotechnology, 3D printing and genetics and biotechnology are all building on and amplifying one another…”

The World Economic Forum (WEF) published an analysis today on the technological and sociological drivers of employment.

The report, titled The Future of Jobs, validates the accelerating impact of technology on global employment trends, and also highlights serious concerns that job growth in certain industries is still very much outpaced by large scale declines in other industries.

The report surveyed senior executives and chief human resources officers of various companies “representing more than 13 million employees across 9 broad industry sectors in 15 major developed and emerging economies and regional economic areas.”

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People with a family history of some inheritable diseases like cystic fibrosis can now be tested to see if they carry the genes for the condition. If neither parent has the disease, but both carry the corresponding gene or genes, the odds of having a child with the condition are higher.

Cambridge diagnostics company Good Start Genetics has partnered with Helix, a startup in California, to bring its genetic tests to a bigger market.

People with a family history of some inheritable diseases like cystic fibrosis can now be tested to see if they carry the genes for the condition. If neither parent has the disease, but both carry the corresponding gene or genes, the odds of having a child with the condition are higher.

Good Start is among the companies that specializes in such “carrier testing” and sells tests for 23 diseases, including cystic fibrosis and spinal muscular atrophy.

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A new algorithm has been developed that will drastically reduce the time and effort needed to create induced pluripotent stem cells (iPSCs). As a result of this breakthrough, we can expect a dramatic revolution in regenerative medicine in the near future.

What if you could directly reprogram cells to develop into whatever you wished? What if you could take an undifferentiated, incipient cell, full of the unrealized potential to become any one of the many specialized cells in the human body, and nudge it into becoming ocular tissue, or neural cells, even a new heart to replace an old or damaged one?

This is the promise afforded by Mogrify, the result of the application of computational and mathematical science to the problems of medicine and biology. It was developed by an international collaboration of researchers from the Duke-NUS Medical School in Singapore, the University of Bristol in the United Kingdom, Monash University in Australia, and RIKEN in Japan. The new research was published online in the journal Nature Genetics.

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The real opportunities of our future is when we truly integrate technology and genetics/ healthcare together to the point that technology benefits from learning and evolving from what we do in genetics/ healthcare; and genetics/ healthcare truly evolve through technology discoveries and evolution. Does this sound like singularity? Yes; however, this is when we truly see some amazing advancements in both fields. And, several investors (even in Silicon Valley) are investing in technology that is positioned to focus on evolving technology through healthcare.

Scientists have been quietly working for decades to crack the genetic codes that allow humans to live forever, or at least significantly longer.

And judging by the bits of information on this research that is beginning to leak into the mainstream of human discourse, the idea may no longer be far-fetched.

Stuart Kim, a genetics professor at Stanford University, recently appeared on Fox Business News speaking about his work in the field of “gene therapy.”

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CRISPR/Cas9 has been touted as an almost magical technology in the news—and rightly so. The technique allows scientists to alter the DNA of living cells and, it’s hoped, achieve a longstanding goal of science to treat disease at the genetic level.

That’s a really big deal.

An estimated 6,000 diseases are caused by genetic mutations, and only 5% can be treated. Take sickle-cell anemia, for example. Often deadly, it is caused by a single mutation in one of the human body’s three billion DNA base pairs. It’s a small, well-understood error in the genetic code, but so far we have been helpless to repair it.

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Interesting perspective of the world and globalization.

It is my belief that we are heading toward a blend of Islandization and Commonization. World transformation is powered first and foremost by the mega-driver of technology, which in turn is central to both of these worlds. The most significant change in the past seven years of world history is that we have entered into a period of sustained technological progress. I fully expect in coming years further breakthroughs in areas including alternative energy, biotechnology and artificial intelligence that dramatically change our economies and our societies.

Unfortunately, I am less sure that technological change will be positive. The exploitation by violent extremists of social media is a case in point of the double-edge that new technologies can bring. This is an extremely disruptive and dislocating time for individuals, organizations and governments alike. The net gain of technology will almost certainly be positive, but there will be winners and losers, and losers will not necessarily go quietly. Nor will the winners necessarily perceive objective gain as actual gain. And some new technologies, such as the gene-editing powers of CRISPR, point to a highly uncertain future.

In our days together in Davos, I will focus my conversations on this new age of exploration in a post-globalization world. As the next global order takes hold, organizational foresight and agility will be critical in determining winners and losers in the new global operating environment.

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Yeah, he’s turned into quite the man-of-panic as of late.

Stephen Hawking is at it again, saying it’s a “near certainty” that a self-inflicted disaster will befall humanity within the next thousand years or so. It’s not the first time the world’s most famous physicist has raised the alarm on the apocalypse, and he’s starting to become a real downer. Here are some of the other times Hawking has said the end is nigh—and why he needs to start changing his message.

Speaking to the Radio Times recently ahead of his BBC Reith Lecture, Hawking said that ongoing developments in science and technology are poised to create “new ways things can go wrong.” The scientist pointed to nuclear war, global warming, and genetically-engineering viruses as some of the most serious culprits.

“Although the chance of a disaster on planet Earth in a given year may be quite low, it adds up over time, becoming a near certainty in the next thousand or ten thousand years,” he was quoted as saying. “By that time we should have spread out into space, and to other stars, so it would not mean the end of the human race. However, we will not establish self-sustaining colonies in space for at least the next hundred years, so we have to be very careful in this period.”

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In less than 4 yrs. 5 million jobs will be lost is the prediction.

A new report predicts a loss of 5 million jobs in the next five years because of technological advances, but don’t blame it all on the robots.

The other culprits: artificial intelligence, 3-D printers and advances in genetics, biotech and more.

The World Economic Forum, which is holding its annual meeting in Davos this week, in its report details the effects of modern technology on the labor market, for better or for worse. It says “the fourth industrial revolution” will be “more comprehensive and all-encompassing than anything we have ever seen.”

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Although the recent article and announcement of Josiah Zayner (CA scientist) new do it yourself gene editing kit for $120 sent shock waves across industry as well as further raised the question “how do we best put controls in place to ensure ethics and prevent disaster or a crisis?”; this genie truly is out of the bottle. Because Josiah created this easily in his own kitchen, it can be replicated by many others in their own homes. What we have to decide is how to best mitigate it’s impact. Black markets & exotic animal, etc. collectors around the world will pay handsomely for this capability and raise the stakes of the most bizarre animals (deadly and non-deadly) to be created for their own profits and amusements.

BURLINGAME, Calif. — On the kitchen table of his cramped apartment, Josiah Zayner is performing the feat that is transforming biology. In tiny vials, he’s cutting, pasting and stirring genes, as simply as mixing a vodka tonic. Next, he slides his new hybrid creations, living in petri dishes, onto a refrigerator shelf next to the vegetables. And he’s packaging and selling his DIY gene-editing technique for $120 so that everyone else can do it, too.

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