Exclusive: UK scientist says giving booster jabs rather than sharing doses equitably will cause hundreds of thousands of avoidable deaths.
The U.S. Preventive Services Task Force’s proposed changes to recommendations for using low-dose aspirin to prevent a first heart attack or stroke closely align with guidelines from the American College of Cardiology and the American Heart Association.
In a paper published in Scientific Reports, academics at the University of Surrey have discovered that biological cells generate an electric field voltage that appears outside and not just within, meaning each cell acts as a tiny electrode. Since this voltage impacts how cells interact with their environment, including the way cells stick to one another, this has significant potential implications for future medical treatments.
Since the 1790s, scientists have known that electricity plays a role in the function of life, with the discovery in the 1940s that every cell contains a voltage that controls many of its functions. This is particularly the case in muscle and nerve cells but has also been shown to play an important role in diseases such as cancer.
However, until now, this voltage has always been understood to be contained within the cell. Through intricate experiments with red blood cells, the Surrey-led research team has shown that the voltage appears outside the cell as well. This means that cells effectively act as tiny transmitters, electrically changing the environment around them. Similar results in other types of biological cells could play a significant role in determining new types of medical treatment.
Imperial researchers have found that variability between brain cells might speed up learning and improve the performance of the brain and future artificial intelligence (AI).
The new study found that by tweaking the electrical properties of individual cells in simulations of brain networks, the networks learned faster than simulations with identical cells.
They also found that the networks needed fewer of the tweaked cells to get the same results and that the method is less energy-intensive than models with identical cells.
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The research is published in Nature Communications.
Why is a neuron like a snowflake?
The brain is made up of billions of cells called neurons, which are connected by vast ‘neural networks’ that allow us to learn about the world. Neurons are like snowflakes: they look the same from a distance but on further inspection it’s clear that no two are exactly alike.
Back in June, the investor advocacy nonprofit As You Sow had filed a shareholder resolution with the Securities and Exchange Commission requesting that Microsoft examine the “environmental and social benefits of making its devices more easily repairable through measures such as the public provision of tools, parts, and repair instructions.” Prior to that resolution, Microsoft—like many tech companies—had essentially rigged the game so that its devices could only be fixed at authorized shops, effectively creating a monopoly on repairs that stifled consumer freedom and made everyone’s lives harder.
But on Thursday, Grist reported that Microsoft has now made a series of critical concessions as a result of that resolution, including a pledge to hire an independent consultant to study the ways increasing access to the parts and information could cut down on electronic waste and lessen damaging environmental impacts, and a commitment to acting on the findings of that study by the end of 2022.
“This is an encouraging step by Microsoft to respond to the upswell of federal and state activity in the right to repair movement,” Kelly McBee, waste program coordinator at As You Sow, said in a press release. “Excitingly, this agreement will begin to allow consumers to repair their Microsoft devices outside the limited network of authorized repair shops.”
Researchers in Japan have developed a vaccination strategy in mice that promotes the production of antibodies that can neutralize not only SARS-CoV-2 but a broad range of other coronaviruses as well. If successfully translated to humans, the approach, to be published October 8 in the Journal of Experimental Medicine, could lead to the development of a next-generation vaccine capable of preventing future coronavirus pandemics.
The SARS-CoV-2 virus responsible for COVID-19 enters human cells by using its spike protein to bind to a cell surface receptor called ACE2. The receptor-binding domain of the spike protein consists of two parts: a “core” region that is very similar in all coronaviruses, and a more specialized “head” region that mediates binding to ACE2.
Antibodies that recognize the head region of the spike receptor-binding domain can block the entry of SARS-CoV-2 into cells but offer little protection against other coronaviruses, such as the SARS-CoV-1 virus responsible for the severe acute respiratory syndrome outbreak of 2002. Antibodies that recognize the core region of the spike receptor-binding domain, in contrast, can prevent the entry of various coronaviruses into human cells. Unfortunately, however, individuals exposed to the viral spike protein tend to produce lots of antibodies against the head region but few, if any, antibodies that recognize the core region.
