Lifeboat Foundation: Safeguarding Humanity
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Category: finance

Dr. Aubrey de Grey from the SENS Research Foundation was kind enough to talk in support of CellAge and their campaign on Lifespan.io

We are developing tools to help researchers accurately target and remove dysfunctional cells in the body that have entered a state called “senescence”, and thereby assist in restoring it to youthful functionality. Please subscribe, share, and fund our campaign today! ►Campaign Link: https://www.lifespan.io/campaigns/cellage-targeting-senescent-cells-with-synthetic-biology/ ►Subscribe: https://www.youtube.com/user/LifespanIO?sub_confirmation=1

Our society has never aged more rapidly – one of the most visible symptoms of the changing demographics is the exponential increase in the incidence of age-related diseases, including cancer, cardiovascular diseases and osteoarthritis. Not only does aging have a negative effect on the quality of life among the elderly but it also causes a significant financial strain on both private and public sectors. As the proportion of older people is increasing so is health care spending. According to a WHO analysis, the annual number of new cancer cases is projected to rise to 17 million by 2020, and reach 27 million by 2030. Similar trends are clearly visible in other age-related diseases such as cardiovascular disease. Few effective treatments addressing these challenges are currently available and most of them focus on a single disease rather than adopting a more holistic approach to aging.

Recently a new approach which has the potential of significantly alleviating these problems has been validated by a number of in vivo and in vitro studies. It has been demonstrated that senescent cells (cells which have ceased to replicate due to stress or replicative capacity exhaustion) are linked to many age-related diseases. Furthermore, removing senescent cells from mice has been recently shown to drastically increase mouse healthspan (a period of life free of serious diseases).

Here at CellAge we are working hard to help translate these findings into humans!

CellAge, together with a leading synthetic biology partner, Synpromics, is going to develop synthetic promoters which are specific to senescent cells (SeneSENSE), as promoters that are currently being used to track senescent cells are simply not good enough to be used in therapies. The most prominently used p16 gene promoter has a number of limitations, for example. As our primary mission is to expand the interface between synthetic biology and aging research as well as drive translational research forward, we will offer senescence reporter assay to academics for free. We predict that in the very near future this assay will be also used as a quality control step in the cell therapy manufacturing process to make cell therapies safer!

As our secondary goal, we will focus on validating gene therapies for senescent cell eradication (SeneHEALTH) – initially for patients with progeroid syndromes, then for patients who underwent radiotherapy (during which the number of senescent cells are increased) or developed age-related disease and eventually for healthy individuals.

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Glad that the author is highlighting the need for investment; however, the US government has had a quantum network since 1991. Wall Street, various overseas banks, ISPs, etc. well over a year to 2 years ago. And, tech has invested in QC for a decade or longer. So, the article raises the need for investing in QC; however, the investing is no longer experimental as it is now about the daily usage of this technology as well as planning for technical transformation that is coming in the next 5 to 7 years.

Researchers led by Lockheed Martin and IBM are pushing quantum computing prototypes and military applications.

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Nantero Inc., the nanotechnology company developing next-generation memory using carbon nanotubes, today announced the closing of an over $21 million financing round. The lead investor in the round was Globespan Capital Partners and also included participation from both new and existing strategic and financial investors. Nantero currently has more than a dozen partners and customers in the consumer electronics, enterprise systems, and semiconductor industries actively working on NRAM®. The new funding will enable the company to support these partners in bringing multiple products into the market, while also enabling new customers to begin development. This financing round brings the total invested in Nantero to date to over $110 million.

“This round enables Nantero to accelerate its pace in product development, especially of its multi-gigabyte DDR4-compatible memory product,” said David Poltack, Managing Director, Globespan Capital Partners. “Nantero has multiple industry-leading customers who would like to receive NRAM even sooner. The fact that several of these customers, as well as key partners in the ecosystem, have decided to also invest in Nantero is a strong sign of confidence given how well they know Nantero and its product from years of working together.”

“The customer traction we’ve achieved at Nantero has been overwhelming, as evidenced by our recent announcement that NRAM had been selected by both Fujitsu Semiconductor and Mie Fujitsu Semiconductor,” said Greg Schmergel, Co-Founder & CEO of Nantero. “With this additional funding, we will be able to help these existing customers speed their time to market while also supporting the many other companies that have approached us about using Nantero NRAM in their next generation products.”

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Money makes the world go round, or so they say. Payments, investments, insurance and billions of transactions are the beating heart of a fractal economy, which echoes the messy complexity of natural systems, such as the growth of living organisms and the bouncing of atoms.

Financial systems are larger than the sum of their parts. The underlying rules that govern them might seem simple, but what surfaces is dynamic, chaotic and somehow self-organizing. And the blood that flows through this fractal heartbeat is data.

Today, 2.5 exabytes of data are being produced daily. That number is expected to grow to 44 zettabytes a day by 2020 (Source: GigaOm). This data, along with interconnectivity, correlation, predictive analytics and machine learning, provides the foundation for our AI-powered future.

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“It’s a fairly concise but expansive vision of what is possible to build with open public blockchains.”

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In Brief:

  • IBM surveyed 200 global banks and financial institutions as part of two recently released studies.
  • The widespread use of Blockchain could lead to more secure, efficient banking experiences.

Recent reports by IBM have revealed that by 2017, 15 percent of big banks worldwide and 14 percent of major financial institutions will be using Blockchain technology.

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I believe we’re really looking at less than 10yrs given the speed of evolution of QC to date. Instead of two new QC discoveries each year to advance QC; we’re now seeing 2 new discoveries every 2 months now not to mention China and US advancements on networking and communications and scalable QC for devices which Google plans to release their QC device in 2017.

Quantum computers could bring about a quantum leap in processing power, with countless benefits for fields like data science and AI. But there’s also a dark side: this extra power will make it simple to crack the encryption keeping everything from our emails to our online banking secure.

A recent report from the Global Risk Institute predicted that there is a one in seven chance vital cryptography tools will be rendered useless by 2026, rising to a 50% chance by 2031. In the meantime, hackers and spies can hoover up data encrypted using current approaches and simply wait until quantum computers powerful enough to crack the code have been developed.

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Longevity a challenge or an opportunity?

This autumn, The Economist Events will bring global leaders from business, finance and health care together with policymakers to explore the opportunities of an ageing world.

Together they will discuss how best to adapt financial products and realign business and public policies in ways that will drive economic growth and mitigate problems that ageing societies could otherwise bring.

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In 5 years if you’re looking at QC in your future state roadmap; then welcome to the dinosaur age of technology.

BEIJING: China today launched a 712-km quantum communication line, stated to be the worlds longest secure telecommunications network, which boasts of ultra-high security making it impossible to wiretap, intercept or crack the information transmitted through them.

The new quantum communication line links Hefei, capital of Anhui province, to Shanghai, the countrys financial hub.

It is part of a 2,000-km quantum communication line connecting Beijing and Shanghai, according to Chen Yuao, professor at the University of Science and Technology of China (USTC) in Hefei and chief engineer of the Beijing-Shanghai quantum communication line.

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Tesla completed its $2.6 billion acquisition of SolarCity this week, and, to celebrate, the company has announced a major solar energy project: wiring up the whole island of Ta’u in American Samoa. Previously, the island ran on diesel generators, but over the past year Tesla has installed a microgrid of solar energy panels and batteries that will supply “nearly 100 percent” of power needs for Ta’u’s 600 residents.

The project seems intended to show off the potential benefits of the SolarCity acquisition, with Ta’u’s microgrid comprised of 5,328 solar panels from SolarCity and Tesla, along with 60 Tesla Powerpacks batteries for storage. But buying SolarCity remains a risky move for Tesla, with the purchase including billions of dollars of debt for a company that’s far from profitable (SolarCity spends $6 for every $1 it makes in sales). Nevertheless, Tesla CEO Elon Musk describes the acquisition as “blindingly obvious” — a necessary step in his so-called “Master Plan” to integrate clean energy generation and storage.

The project in Ta’u shows the benefit of this. It was funded by American Samoan and US authorities (including the Department of Interior), and Tesla says it will offset the island’s use of more than 109,500 gallons of diesel per year, as well as the expense of shipping that fuel in. Confusingly, the “Factoring in the escalating cost of fuel, along with transporting such mass quantities to the small island, the financial impact is substantial,” said Tesla in a blog post.

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