Toggle light / dark theme

Organic transistors that can simulate basic synaptic functions and act as biomimetic devices are advantageous for next generation bioelectronics. Here, the authors realize non-volatile organic electrochemical transistors with optimized performance required for associative learning circuits.

Scientists used to perform experiments by stirring biological and chemical agents into test tubes.

Nowadays, they automate research by using the size of postage stamps. In these tiny devices, millions of microscopic particles are captured in droplets of water, each droplet serving as the “test tube” for a single experiment. The chip funnels these many droplets, one at a time, through a tiny channel where a laser probes each passing droplet to record thousands of experimental results each second.

These chips are used for such things as testing new antibiotics, screening drug compounds, sequencing the DNA and RNA of single cells, and otherwise speeding up the pace of scientific discovery.

To combat this, Li and his team at Harvard have designed their solid-state battery with a multilayer approach that stacks its materials of varying stabilities between the anode and cathode. Much like a sandwich. This multi-material battery sandwich helps alleviate the penetration of lithium dendrites by controlling and containing them rather than preventing them altogether.

As you can see from the image above, the Harvard team has simplified its battery design to a form that’s more our speed. In this case, a BLT sandwich. The top slice of bread represents the lithium-metal anode, followed by lettuce appropriately representing a coating of graphite. The two layers of tomatoes represent the first electrolyte, protecting the delicious middle layer of bacon as the second electrolyte. Everything sits upon the bottom slice of bread, or the cathode. Is anyone else suddenly hungry for batteries?

In this design, dendrites are able to grow through the graphite (lettuce) and first electrolyte (tomato) but are halted when they reach the second electrolyte (bacon), thus preventing the dendrites from shorting the entire battery. This multilayer approach provokes chemistry that makes the second electrolyte too tight for the dendrites to penetrate. Furthermore, the Harvard researchers say this same chemistry can backfill the holes made by dendrites, essentially making the solid-state battery self-healing. Is there anything better than a sandwich that can regenerate itself? Honestly.

Nuclear Nonproliferation, Cooperative Threat Reduction and WMD Terrorism — Dr. Natasha Bajema, Director, Converging Risks Lab, The Council on Strategic Risks.


Dr. Natasha Bajema, is a subject matter expert in nuclear nonproliferation, cooperative threat reduction and WMD terrorism, and currently serves as Director of the Converging Risks Lab, at The Council on Strategic Risks, a nonprofit, non-partisan security policy institute devoted to anticipating, analyzing and addressing core systemic risks to security in the 21st century, with special examination of the ways in which these risks intersect and exacerbate one another.

The Converging Risks Lab (CRL) is a research and policy development-oriented program designed to study converging, cross-sectoral risks in a rapidly-changing world, which brings together experts from multiple sectors of the security community, to ask forward-thinking questions about these converging risks, and to develop anticipatory solutions.

Dr. Bajema is also Founder and CEO of Nuclear Spin Cycle, a publishing and production company specializing in national security, entertainment, and publishing.

Prior to this, Dr. Bajema was at the Center for the Study of Weapons of Mass Destruction at the National Defense University, serving as Director of the Program for Emerging Leaders (PEL), as well as serving long-term detail assignments serving in various capacities in the Office of the Secretary of Defense, Acquisitions, Technology and Logistics, Nuclear, Chemical and Biological Defense Programs and in Defense Nuclear Nonproliferation at Department of Energy’s National Nuclear Security Administration.

Prior to joining the Center, Dr. Bajema was a Research Associate at the Center on International Cooperation at New York University, where she supported research staff of the High-Level Panel on Threats, Challenges and Change established by the UN Secretary-General. She has also served as a Junior Political Officer in the Weapons of Mass Destruction Branch of the Department for Disarmament Affairs at the United Nations.

Dr. Bajema’s publications include two co-edited volumes entitled Terrorism and Counterterrorism, and Weapons of Mass Destruction and Terrorism, both of which were published by McGraw Hill. She has also published the novels Bionic Bug, Rescind Order, Genomic Data, and Project Gecko.

Dr. Bajema holds an M.A. in international policy from the Monterey Institute of International Studies and a PhD in international relations from the Fletcher School of Law and Diplomacy.

Only one in three fertilizations leads to a successful pregnancy. Many embryos fail to progress beyond early development. Cell biologists at the Max Planck Institute (MPI) for Biophysical Chemistry in Göttingen (Germany), together with researchers at the Institute of Farm Animal Genetics in Mariensee and other international colleagues, have now developed a new model system for studying early embryonic development. With the help of this system, they discovered that errors often occur when the genetic material from each parent combines immediately after fertilization. This is due to a remarkably inefficient process.

Human somatic cells typically have 46 , which together carry the genetic information. These chromosomes are first brought together at fertilization, 23 from the father’s sperm, and 23 from the mother’s egg. After fertilization, the parental chromosomes initially exist in two separate compartments, known as pronuclei. These pronuclei slowly move towards each other until they come into contact. The pronuclear envelopes then dissolve, and the parental chromosomes unite.

The majority of human embryos, however, end up with an incorrect number of chromosomes. These embryos are often not viable, making erroneous genome unification a leading cause of miscarriage and infertility.

7:01 they talk about Church’s comments of ending aging by 2030. Also this appears to be a part one.


In this video Professor Church talks about his theory of aging and touches on his ideas on the future of aging.

George Church is the Robert Winthrop Professor of Genetics at Harvard Medical School, a Professor of Health Sciences and Technology at Harvard and MIT. Professor Church helped initiate the Human Genome Project in 1984 and the Personal Genome Project in 2005. He is widely recognized for his innovative contributions to genomic science and his many pioneering contributions to chemistry and biomedicine. He has co-authored 580 paper, 143 patent publications & the book “Regenesis”.

George Church Links.
Professor Church’s Lab at Harvard.
https://arep.med.harvard.edu/

Professor Church’s Book on Amazon.
Regenesis: How Synthetic Biology Will Reinvent Nature and Ourselves.
https://amzn.to/3vTAVKo.

Twitter Link.
https://twitter.com/geochurch.
***********************************************************************************
If you would like to support our channel, we’d love a coffee…thank you! https://www.buymeacoffee.com/mhealthspan.

#TheoryOfAging #GeorgeChurch #Harvard

For the first time, a spacecraft on another planet has recorded the sounds of a separate spacecraft. NASA’s Perseverance Mars rover used one of its two microphones to listen as the Ingenuity helicopter flew for the fourth time on April 30, 2021. A new video combines footage of the solar-powered helicopter taken by Perseverance’s Mastcam-Z imager with audio from a microphone belonging to the rover’s SuperCam laser instrument.

The laser zaps rocks from a distance, studying their vapor with a spectrometer to reveal their chemical composition. The instrument’s records the sounds of those laser strikes, which provide information on the physical properties of the targets, such as their relative hardness. The microphone can also record , like the Martian wind.

With Perseverance parked 262 feet (80 meters) from the helicopter’s takeoff and landing spot, the rover mission wasn’t sure if the microphone would pick up any sound of the flight. Even during flight, when the helicopter’s blades spin at 2537 rpm, the sound is greatly muffled by the thin Martian atmosphere. It is further obscured by Martian wind gusts during the initial moments of the flight. Listen closely, though, and the helicopter’s hum can be heard faintly above the sound of those winds.

Many people with diabetes endure multiple, painful finger pricks each day to measure their blood glucose. Now, researchers reporting in ACS Sensors have developed a device that can measure glucose in sweat with the touch of a fingertip, and then a personalized algorithm provides an accurate estimate of blood glucose levels.

According to the American Diabetes Association, more than 34 million children and adults in the U.S. have diabetes. Although self-monitoring of blood glucose is a critical part of diabetes management, the pain and inconvenience caused by finger-stick blood sampling can keep people from testing as often as they should.

The researchers made a touch-based sweat glucose sensor with a polyvinyl alcohol hydrogel on top of an electrochemical sensor, which was screen-printed onto a flexible plastic strip. When a volunteer placed their fingertip on the sensor surface for 1 minute, the hydrogel absorbed tiny amounts of sweat. Inside the sensor, glucose in the sweat underwent an enzymatic reaction that resulted in a small electrical current that was detected by a hand-held device.