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“What’s so exciting about this result is that it suggests that these types of nanowire networks can be tuned into regimes with diverse, brain-like collective dynamics, which can be leveraged to optimize information processing,” said Zdenka Kuncic from the University of Sydney in a press release.

Today’s deep neural networks already mimic one aspect of the brain: its highly interconnected network of neurons. But artificial neurons behave very differently than biological ones, as they only carry out computations. In the brain, neurons are also able to remember their previous activity, which then influences their future behavior.

This in-built memory is a crucial aspect of how the brain processes information, and a major strand in neuromorphic engineering focuses on trying to recreate this functionality. This has resulted in a wide range of designs for so-called “memristors”: electrical components whose response depends on the previous signals they have been exposed to.

Long vid. Slight annotation in the comments. A few takaways I liked: We need to move to human data instead of mice. People’s attitude towards life extension should change drastically soon. There is human data among this group and have released it, will keep following it, and some to be released soon. Sinclair thinks he can start primate trials this year. And overall everyone is optimistic.


A couple of weeks ago Avi Roy, alongside Nathan Cheng & Laura Minquini, hosted the Longevity Panel discussion, which assembled some of the biggest scientists in the field currently working on reversing aging.

This discussion was intended to illuminate how they are approaching longevity and to know if we are any closer in achieving it.

The talk was split into two sections: the first being open discussion guided by questions from the hosts. The talk was then opened up to the floor, allowing audience questions. Part 1 will provide the transcript from the first section of the Longevity Panel. Enjoy!

You can check out the full transcript, with addition links on the Gowing Life website: https://www.gowinglife.com/longevity-panel-the-scientists-working-on-reversing-aging-part-1/
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The questions:
05:35 — How do you plan on reversing aging?

14:52 — If we want to reverse aging or slow it, what are the most promising approaches to measuring biological aging and the effectiveness of the therapeutic interventions that we’re developing?

28:28 — In 1969, gerontologist Alex Comfort suggested that life expectancy, not simply maximum lifespan, could be extended to 120 years within the next 20 years. That didn’t happen because he obviously is not with us anymore. What will be different this time as we try to get people interested in longevity or promise them that this is imminent in some way or form?

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The story of humanity is progress, from the origins of humanity with slow disjointed progress to the agricultural revolution with linear progress and furthermore to the industrial revolution with exponential almost unfathomable progress.

This accelerating rate of change of progress is due to the compounding effect of technology, in which it enables countless more from 3D printing, autonomous vehicles, blockchain, batteries, remote surgeries, virtual and augmented reality, robotics – the list can go on and on. These devices in turn will lead to mass changes in society from energy generation, monetary systems, space colonization, automation and much more!

This trajectory of progress is now leading us into a time period that is, “characterized by a fusion of technologies that is blurring the lines between the physical, digital and biological spheres”, called by many the technological revolution or the 4th industrial revolution — in which everything will change, from the underlying structure and fundamental institutions of society to how we live our day-to-day lives.

00:00 Intro.
01:30 Pillar 1 – Computing.
05:02 Pillar 2 – Global Connectivity.
08:08 Pillar 3 – Big Data.
09:48 Pillar 4 – AI
11:55 The Technological Revolution.

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Over the past ten years, the number of known and named viruses has exploded, owing to advances in the technology for finding them, plus a recent change to the rules for identifying new species, to allow naming without having to culture virus and host. One of the most influential techniques is metagenomics, which allows researchers to sample the genomes in an environment without having to culture individual viruses. Newer technologies, such as single-virus sequencing, are adding even more viruses to the list, including some that are surprisingly common yet remained hidden until now. It’s an exciting time to be doing this kind of research, says Breitbart. “I think, in many ways, now is the time of the virome.”


SARS-CoV-2 is just one of nonillions of viruses on our planet, and scientists are rapidly identifying legions of new species.

Rapamycin consistently shows lifespan extension in mice and in my opinion, is the most exciting molecule to possibly extend healthspan in humans. This video dives into the data.

Thanks for watching, I hope you enjoyed the content and found it genuinely useful.
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Three years ago, Arthur Ashkin won the Nobel Prize for inventing optical tweezers, which use light in the form of a high-powered laser beam to capture and manipulate particles. Despite being created decades ago, optical tweezers still lead to major breakthroughs and are widely used today to study biological systems.

However, optical tweezers do have flaws. The prolonged interaction with the can alter molecules and particles or damage them with excessive heat.

Researchers at The University of Texas at Austin have created a new version of optical tweezer technology that fixes this problem, a development that could open the already highly regarded tools to new types of research and simplify processes for using them today.

Scientists have given the all-clear.


A new study from U.S. Army Research Lab (ARL) scientists reveals there’s nothing stopping the military from producing walking combat vehicles—at least from a power perspective, anyway. The research shows legs use essentially the same amount of power as wheels or tracks, so there’s no disadvantage to using them.

In the PLoS ONE study, scientists say both artificial and biological locomotion systems—literally from 1 gram to 35-ton vehicles—have approximately the same power requirements to move a unit of mass over land. Animals or machines using legs, wheels, or tracks use the same amount of energy.

Biological systems are dynamical, constantly exchanging energy and matter with the environment in order to maintain the non-equilibrium state synonymous with living. Developments in observational techniques have allowed us to study biological dynamics on increasingly small scales. Such studies have revealed evidence of quantum mechanical effects, which cannot be accounted for by classical physics, in a range of biological processes. Quantum biology is the study of such processes, and here we provide an outline of the current state of the field, as well as insights into future directions.

Quantum mechanics is the fundamental theory that describes the properties of subatomic particles, atoms, molecules, molecular assemblies and possibly beyond. Quantum mechanics operates on the nanometre and sub-nanometre scales and is at the basis of fundamental life processes such as photosynthesis, respiration and vision. In quantum mechanics, all objects have wave-like properties, and when they interact, quantum coherence describes the correlations between the physical quantities describing such objects due to this wave-like nature.

In photosynthesis, respiration and vision, the models that have been developed in the past are fundamentally quantum mechanical. They describe energy transfer and electron transfer in a framework based on surface hopping. The dynamics described by these models are often ‘exponential’ and follow from the application of Fermi’s Golden Rule [1, 2]. As a consequence of averaging the rate of transfer over a large and quasi-continuous distribution of final states the calculated dynamics no longer display coherences and interference phenomena. In photosynthetic reaction centres and light-harvesting complexes, oscillatory phenomena were observed in numerous studies performed in the 1990s and were typically ascribed to the formation of vibrational or mixed electronic–vibrational wavepackets.