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DNA Damage Leads to Epigenetic Alterations

Posted in biotech/medical, genetics, life extension

A team of researchers, including Dr. David Sinclair, has recently made a new study available as a preprint prior to peer review and publication in the journal Cell.

DNA damage and the double-strand break

Two of the primary hallmarks of aging are genomic instability, which consists of damage to our DNA, and epigenetic alterations, which are the changes in gene expression that occur with aging and are harmful to normal cell function.

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