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Cancer-targeting compound could be a breakthrough in treating brain tumors

A new compound discovered by scientists at Scripps Research may prove to be a powerful weapon in the fight against one of the most aggressive and deadly types of cancer. Just like the cancer it fights, the compound is incredibly strong, selectively targeting the cells that allow glioblastoma multiforme (GBM) to rapidly take over the brain.

The research, which was published in a new paper in Proceedings of the National Academy of Sciences, explains how the stem-like cancer cells of GBM promote growth of the tumor while also aiding it in recurrence even after a patient has had surgery. Stopping these cells from doing their deadly deed is crucial to successful treatment, and the new compound — which the scientists have nicknamed RIPGBM — does just that.

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