Interesting read.
When it comes to delivering drugs, nanoparticles shaped like rods and worms are the best bet for making the daunting journey to the centre of a cell, new Australian research suggests.
A new study published in Nature Nanotechnology has answered a long-standing question that could lead to the design of better drug delivery vehicles: how nanoparticle shape affects the voyage through the cell.
“We were able to show for the first time that nanoparticles shaped like rods and worms were more effective than spherical nanoparticles at traversing intracellular barriers and this enabled them to get all the way into the nucleus of the cell,” says lead author UNSW’s Dr Elizabeth Hinde.
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