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Reversing aging through cellular reprogramming!?

Posted in education, genetics, life extension

Nice lecture with both technical info and analogy.


Latest study from David Sinclair’s lab have used cellular reprogramming to restore vision in aged mice & more! Suggests reversing aging *may* be possible.

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TIMESTAMPS;
Intro — 00:00
Aging is loss of information — 00:45
Correction device & epigenetics — 02:49
Yamanaka factors & OSKM — 04:45
Study results from Sinclair lab — 07:25
Aging reversed? — 10:29
Working model — 12:00
Cellular reprogramming in humans? — 12:36.

REFERENCES;
Lu, Y., Brommer, B., Tian, X. et al. Reprogramming to recover youthful epigenetic information and restore vision. Nature 588, 124–129 (2020). https://doi.org/10.1038/s41586-020-2975-4
In Vivo Amelioration… — https://doi.org/10.1016/j.cell.2016.11.052
Yamanaka — https://doi.org/10.1016/j.cell.2006.07.024
News & Views article — https://www.nature.com/articles/d41586-020-03403-0

Icons in intro; “https://www.freepik.com/free-photos-vectors/background“Background vector created by freepik — www.freepik.com

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