Summary: YKL-40 may be a key player in circadian rhythm disruptions associated with Alzheimer’s disease.

Source: WUSTL

Fractured sleep, daytime sleepiness and other signs of disturbance in one’s circadian rhythm are common complaints of people with Alzheimer’s disease, and the problems only get worse as the disease progresses. But the reason for the link between Alzheimer’s and circadian dysfunction is not well understood.