Recently, a team of researchers, including Professor Judy Campisi, has published an atlas charting the inflammatory senescence-associated secretory phenotype (SASP) [1].

The nature of the SASP

As we grow older, increasing numbers of our cells enter a state known as senescence. Senescent cells no longer divide to support and help maintain the tissues that they are a part of and instead secrete a range of harmful inflammatory signals: the SASP.