Lifeboat Foundation: Safeguarding Humanity
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Month: March 2019

For decades, we’ve thought that memories were formed in two distinct stages—short-term first, then long-term later.

We might be wrong. New research suggests that our brains make two copies of each memory in the moment they are formed. One is filed away in the hippocampus, the center of short-term memories, while the other is stored in cortex, where our long-term memories reside.

These findings, published yesterday in the journal Science, upend more than 50 years of accepted neuroscience, and they’re being hailed by other neuroscientists. Here’s James Gallagher, reporting for BBC News:

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Of all the conditions that affect the elderly, one of the hardest for family and medical providers to deal with is Alzheimer’s disease. This condition impairs memory to the point that some afflicted with the condition can’t remember their loved ones. MIT researchers have found a new potential treatment that has shown promise in testing.

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In February, a group of 16 researchers from Harvard, MIT, and other institutions around the U.S. and Europe launched the nonprofit Academy for Health and Lifespan Research to promote future work, ease collaborations between scientists, and ensure that governments and corporations are making decisions based on the latest facts instead of rumor, speculation, or hype.

Research into extending humanity’s healthy lifespan has been progressing rapidly in recent years. In February, a group of aging and longevity scientists founded a nonprofit to foster the work and serve as a resource for governments and businesses looking to understand the potentially far-reaching implications of a population that lives significantly longer, healthier lives.

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It is often not the lack of a cure, but the lack of will. Many great strides have been made with diabetes, when people stopped trying to develop medicines, and instead focused on how to enable the body to produce insulin.

Restoration of insulin independence and normoglycemia has been the overarching goal in diabetes research and therapy. While whole-organ and islet transplantation have become gold-standard procedures in achieving glucose control in diabetic patients, the profound lack of suitable donor tissues severely hampers the broad application of these therapies. Here, we describe current efforts aimed at generating a sustainable source of functional human stem cell-derived insulin-producing islet cells for cell transplantation and present state-of-the-art efforts to protect such cells via immune modulation and encapsulation strategies.

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Imagine a future where an online dating app doesn’t just match you to potential partners who meet your preferences for age, height and fondness for pinot noir, but to those with whom you’re genetically compatible. Not so much people you’re likely to have physical chemistry with – apps that make dubious claims to do that on the basis of a cheek swab already exist – but those with whom you won’t pass on a devastating genetic disease to your children.

It’s not sexy stuff; certainly not first-date conversation. Most people only discover that they’re among the four per cent who carry the same recessive genetic mutation for a rare condition, such as cystic fibrosis or Tay-Sachs, as their partner when their baby is born with it – or dies from it.

True, couples could find out their genes don’t mix after they’ve decided to have a baby and before they start trying – but how heartbreaking would that be, once they’re already in love? Far simpler never to meet in the first place, and simply to pick from the other 96 per cent with whom they can mate with abandon.

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The questions that kids ask about science aren’t always easy to answer. Sometimes, their little brains can lead to big places that adults forget to explore. That is what inspired our series Science Question From A Toddler, which uses kids’ curiosity as a jumping-off point to investigate the scientific wonders that adults don’t even think to ask about. The answers are for adults, but they wouldn’t be possible without the wonder that only a child can bring. I want the toddlers in your life to be a part of it! Send me their science questions, and they may serve as the inspiration for a column. And now, our toddler …

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The UK project to develop a hypersonic engine that could take a plane from London to Sydney in about four hours is set for a key demonstration.

The Sabre engine is part jet, part rocket, and relies on a novel pre-cooler heat-exchanger technology.

This pre-cooler system will begin a new phase of testing in the next month or so in Colorado, US.

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