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Scientists Identify Gut-Derived Metabolites that Play a Role in Neurodegeneration

Posted in biotech/medical, neuroscience

๐™๐™๐™š ๐™‚๐™ง๐™–๐™™๐™ช๐™–๐™ฉ๐™š ๐˜พ๐™š๐™ฃ๐™ฉ๐™š๐™ง ๐™ค๐™› ๐™๐™๐™š ๐˜พ๐™ž๐™ฉ๐™ฎ ๐™๐™ฃ๐™ž๐™ซ๐™š๐™ง๐™จ๐™ž๐™ฉ๐™ฎ ๐™ค๐™› ๐™‰๐™š๐™ฌ ๐™”๐™ค๐™ง๐™ :

The Neuro-Network.

๐™Ž๐™˜๐™ž๐™š๐™ฃ๐™ฉ๐™ž๐™จ๐™ฉ๐™จ ๐™„๐™™๐™š๐™ฃ๐™ฉ๐™ž๐™›๐™ฎ ๐™‚๐™ช๐™ฉ-๐˜ฟ๐™š๐™ง๐™ž๐™ซ๐™š๐™™ ๐™ˆ๐™š๐™ฉ๐™–๐™—๐™ค๐™ก๐™ž๐™ฉ๐™š๐™จ ๐™ฉ๐™๐™–๐™ฉ ๐™‹๐™ก๐™–๐™ฎ ๐™– ๐™๐™ค๐™ก๐™š ๐™ž๐™ฃ ๐™‰๐™š๐™ช๐™ง๐™ค๐™™๐™š๐™œ๐™š๐™ฃ๐™š๐™ง๐™–๐™ฉ๐™ž๐™ค๐™ฃ

๐™๐™๐™š ๐™™๐™ž๐™จ๐™˜๐™ค๐™ซ๐™š๐™ง๐™ฎ ๐™–๐™™๐™ซ๐™–๐™ฃ๐™˜๐™š๐™จ ๐™ช๐™ฃ๐™™๐™š๐™ง๐™จ๐™ฉ๐™–๐™ฃ๐™™๐™ž๐™ฃ๐™œ ๐™ค๐™› ๐™ฉ๐™๐™š ๐™ง๐™ค๐™ก๐™š ๐™ค๐™› ๐™œ๐™ช๐™ฉ-๐™—๐™ง๐™–๐™ž๐™ฃ ๐™˜๐™ค๐™ข๐™ข๐™ช๐™ฃ๐™ž๐™˜๐™–๐™ฉ๐™ž๐™ค๐™ฃ๐™จ ๐™žโ€ฆ See more.


The discovery advances understanding of the role of gut-brain communications in the development of multiple sclerosis and homes in on a potential therapeutic target

NEW YORK, December 20, 2021 โ€” A New York-based, multi-institutional research team has found high levels of three toxic metabolites produced by gut bacteria in the cerebrospinal fluid and plasma samples of multiple sclerosis (MS) patients. The important findings, published in the journal Brain, further scientistsโ€™ understanding of how gut bacteria can impact the course of neurological diseases by producing compounds that are toxic to nerve cells.

Previously published evidence has supported the concept that an imbalance in the gut microbiotaโ€”the community of organisms that live in the human intestinesโ€”may underly a range of neurological disorders. Researchers also found that certain gut bacteria are either enriched or depleted in MS patients compared to healthy individuals, but it is unclear how these microbes communicate with the brain and affect the neurodegenerative disease process.

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